K Number
K990304
Manufacturer
Date Cleared
1999-07-15

(164 days)

Product Code
Regulation Number
872.3640
Panel
Dental
Reference & Predicate Devices
Predicate For
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
Intended Use

For use in selected fully edentulous and partially edentulous arches

Device Description

The additional components provided for by this 510(k) added to the fixtures, abutments and other components necessary to meet various clinical situations in partially and totally edentulous patients. All implants are root-form uncoated screws and are made from commercially pure titanium. The indications and uses for these additional components are not different from similar components of the predicate device. The application also provides for the use of the Single Tooth Implant System in multiple construction clinical situations.

AI/ML Overview

This submission (K990304) is for additional components (abutments and fixtures) for an existing dental implant system, not a device that would typically have performance criteria measured by a clinical study with specific metrics like sensitivity, specificity, or accuracy. The FDA's review for this type of device focuses primarily on substantial equivalence to a predicate device, material safety, and mechanical integrity rather than diagnostic accuracy or clinical outcomes in the same way an AI/ML device would.

Therefore, the requested information regarding acceptance criteria, study details, expert review, MRMC studies, standalone performance, and ground truth for training and test sets is not applicable to this 510(k) submission.

This submission is a traditional 510(k) for an updated version of a previously approved device (K931767), comprising a list of components made of a known material (commercially pure titanium). The "acceptance criteria" in this context would revolve around demonstrating that the new components meet the same performance standards (e.g., mechanical strength, biocompatibility) as the predicate device and do not introduce new safety or effectiveness concerns. These kinds of evaluations are typically done through bench testing (e.g., fatigue testing, force retention, material characterization) rather than efficacy studies involving patient data and diagnostic performance metrics.

The documentation provided indicates that the "indications and uses for these additional components are not different from similar components of the predicate device." This suggests the primary "study" supporting the submission would be a demonstration of equivalence to the predicate, likely through design comparisons and perhaps limited bench testing for mechanical properties if the design significantly changed from the predicate.

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K990304

JUL 15 1999

510(k) SUMMARY Astra Tech Implants Dental System Additional Components

Submitters Information

Astra Tech, Inc. 430 Bedford Street, Suite 100 Lexington, MA 02173 781-861-7707 Contact: Mr. Niklas Lidskog

Date Prepared

January 12, 1999

Name of Device

Astra Tech Implants - Dental System Additional Abutments and Fixtures for Single Tooth Implant and Standard Implant

Classification Name

Endosseous Implant

Predicate Devices

Similar Devices Previously Approved Under K931767 - Astra Tech Implants - Dental System

Description of Device and Intended Use

The additional components provided for by this 510(k) added to the fixtures, abutments and other components necessary to meet various clinical situations in partially and totally edentulous patients. All implants are root-form uncoated screws and are made from commercially pure titanium. The indications and uses for these additional components are not different from similar components of the predicate device. The application also provides for the use of the Single Tooth Implant System in multiple construction clinical situations.

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List of Components

ProductDiameterPart Number
Uni AbutmentUltrashort, 20 mm22388
Uni AbutmentUltrashort, 45 mm22389
Healing Abutment STShort22586
Healing Abutment STIntermediate22589
Abutment Screw STShort22554
Uni Abutment ST20, 0.0 mm Cuff22674
Uni Abutment ST20, 1.5 mm Cuff22675
Uni Abutment ST20, 3.0 mm Cuff22676
Uni Abutment ST20, 4.5 mm Cuff22677
Uni Abutment ST20, 6.0 mm Cuff22678
Uni Abutment ST45, 0.0 mm Cuff22694
Uni Abutment ST45, 1.5 mm Cuff22695
Uni Abutment ST45, 3.0 mm Cuff22696
Uni Abutment ST45, 4.5 mm Cuff22697
Uni Abutment ST45, 6.0 mm Cuff22698
Fixture ST5.0 mm x 9 mm22821
Fixture ST5.0 mm x 11 mm22822
Fixture ST5.0 mm x 13 mm22823
Fixture ST5.0 mm x 15 mm22824
Fixture ST5.0 mm x 17 mm22825
Fixture ST5.0 mm x 19 mm22826
Fixture ST3.5/4.5, 9 mm22209
Fixture ST3.5/4.5, 9 mm22212

:

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Image /page/2/Picture/1 description: The image shows the logo for the U.S. Department of Health & Human Services. The logo features a stylized caduceus symbol, which is often associated with healthcare. The text "DEPARTMENT OF HEALTH & HUMAN SERVICES - USA" is arranged in a circular pattern around the symbol. The logo is black and white.

Food and Drug Administration 9200 Corporate Boulevard Rockville MD 20850

JUL 15 1999

Mr. Niklas Lidskog Astra Tech, Incorporated 430 Bedford Street, Suite 100 Lexington, Massachusetts 02173

Re : K990304 Modification To Astra Tech Implants - Dental Trade Name: System Regulatory Class: III Product Code: DZE Dated: May 13, 1999 Received: May 17, 1999

Dear Mr. Lidskog:

We have reviewed your Section 510(k) notification of intent to market the device referenced above and we have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act). You may, therefore, market the device, subject to the general controls provisions The general controls provisions of the Act of the Act. include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class II (Special Controls) or class III (Premarket Approval), it may be subject to such additional controls. Existing major regulations affecting your device can be found in the Code of Federal Requlations, Title 21, Parts 800 to 895. A substantially equivalent determination assumes compliance with the Good Manufacturing Practice for Medical Devices: General (GMP) requlation (21 CFR Part 820) and that, through periodic GMP inspections, the Food and Drug Administration (FDA) will verify such assumptions. Failure to comply with the GMP requlation may result in regulatory action. In addition, FDA may publish further announcements concerning your device in the Federal Register.

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Page 2 - Mr. Lidskog

this response to your premarket notification Please note: submission does not affect any obligation you might have under sections 531 through 542 of the Act for devices under the Electronic Product Radiation Control provisions, or other Federal laws or regulations.

This letter will allow you to begin marketing your device as described in your 510(k) premarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus, permits your device to proceed to the market.

If you desire specific advice for your device on our labeling requlation (21 CFR Part 801 and additionally 809.10 for in vitro diagnostic devices), please contact the Office of Compliance at (301) 594-4692. Additionally, for questions on the promotion and advertising of your device, please contact the Office of Compliance at (301) 594-4639. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21 CFR 807.97). Other general information on your responsibilities under the Act may be obtained from the Division of Small Manufacturers Assistance at its toll-free number (800) 638-2041 or (301) 443-6597 or at its internet address "http://www.fda.gov/cdrh/dsmamain.html".

Sincerely yours

Timothy A. Ulatowski

Director Division of Dental, Infection Control, and General Hospital Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

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Page __ 1__of__1_

Not Known 1990304 510(k) Number (if known): Astra Tech Implants - Dental System Device Name: For use in selected fully edentulous and partially Indications for Use: edentulous arches

(PLEASE DO NOT WRITE BELOW THIS LINE - CONTINUE ON ANOTHER PAGE IF NEEDED)

Concurrence of CDRH, Office of Device Evaluation (ODE)

Prescription Line V (Per 21 CFR 801.1091

or

Over-The-Counter Use

(Optional Format 1-2-9G)

Susan Purrs

(Division Sign-Off) Division of Dental, Infection Control, and General Hospital Devices () { } 510(k) Number _

§ 872.3640 Endosseous dental implant.

(a)
Identification. An endosseous dental implant is a prescription device made of a material such as titanium or titanium alloy that is intended to be surgically placed in the bone of the upper or lower jaw arches to provide support for prosthetic devices, such as artificial teeth, in order to restore a patient's chewing function.(b)
Classification. (1) Class II (special controls). The device is classified as class II if it is a root-form endosseous dental implant. The root-form endosseous dental implant is characterized by four geometrically distinct types: Basket, screw, solid cylinder, and hollow cylinder. The guidance document entitled “Class II Special Controls Guidance Document: Root-Form Endosseous Dental Implants and Endosseous Dental Implant Abutments” will serve as the special control. (See § 872.1(e) for the availability of this guidance document.)(2)
Classification. Class II (special controls). The device is classified as class II if it is a blade-form endosseous dental implant. The special controls for this device are:(i) The design characteristics of the device must ensure that the geometry and material composition are consistent with the intended use;
(ii) Mechanical performance (fatigue) testing under simulated physiological conditions to demonstrate maximum load (endurance limit) when the device is subjected to compressive and shear loads;
(iii) Corrosion testing under simulated physiological conditions to demonstrate corrosion potential of each metal or alloy, couple potential for an assembled dissimilar metal implant system, and corrosion rate for an assembled dissimilar metal implant system;
(iv) The device must be demonstrated to be biocompatible;
(v) Sterility testing must demonstrate the sterility of the device;
(vi) Performance testing to evaluate the compatibility of the device in a magnetic resonance (MR) environment;
(vii) Labeling must include a clear description of the technological features, how the device should be used in patients, detailed surgical protocol and restoration procedures, relevant precautions and warnings based on the clinical use of the device, and qualifications and training requirements for device users including technicians and clinicians;
(viii) Patient labeling must contain a description of how the device works, how the device is placed, how the patient needs to care for the implant, possible adverse events and how to report any complications; and
(ix) Documented clinical experience must demonstrate safe and effective use and capture any adverse events observed during clinical use.