K Number
K981043
Device Name
DIALYSOL-ACID CONCENTRATE LIQUID, GRANUSOL-ACID CONCENTRATE POWDER, RENALSOL-ACETATE CONCENTRATE LIQUID & POWDER, BIOSOL
Date Cleared
1998-05-26

(67 days)

Product Code
Regulation Number
876.5820
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP Authorized
Intended Use
THIS CONCENTRATE IS FORMULATED TO BE USED WITH A THREE STREAM HEMODIALYSIS MACHINE WHICH IS CALIBRATED FOR ACID AND BICARBONATE CONCENTRATES. THIS CONCENTRATE IS FORMULATED TO BE USED WITH A TWO STREAM HEMODIALYSIS MACHINE CALIBRATED TO AN ACETATE CONCENTRATED DILUTION RATIO OF 1:34 THIS CONCENTRATE IS FORMULATED TO BE USED WITH A THREE STREAM HEMODIALYSIS MACHINE WHICH IS CALIBRATED FOR ACID AND BICARBONATE CONCENTRATES.
Device Description
Dialysol, Granusol, Renalsol and Biosol Liquid and Powder Dialysate Concentrate
More Information

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Not Found

No
The summary describes dialysate concentrates for hemodialysis machines and does not mention any AI or ML components.

Yes
The device is a concentrate for hemodialysis machines, which are used to treat kidney failure, thus making it a therapeutic device.

No
The concentrates described are for use with hemodialysis machines, which are therapeutic devices, not diagnostic ones. They are formulated to be used in the dialysis process, not for diagnosing conditions.

No

The device description clearly states "Liquid and Powder Dialysate Concentrate," indicating a physical substance, not software.

Based on the provided information, this device is not an IVD (In Vitro Diagnostic).

Here's why:

  • Intended Use: The intended use clearly states that the concentrate is formulated to be used with hemodialysis machines. Hemodialysis is a process that filters blood outside the body, which is a therapeutic procedure, not a diagnostic test performed on samples of bodily fluids or tissues.
  • Device Description: The device is described as "Dialysol, Granusol, Renalsol and Biosol Liquid and Powder Dialysate Concentrate." This is a substance used in the hemodialysis process, not a test kit or instrument for analyzing biological samples.
  • Lack of IVD Indicators: There is no mention of analyzing biological samples, diagnosing conditions, or providing information about a patient's health status based on in vitro testing.

Therefore, this device is a component used in a therapeutic medical procedure (hemodialysis), not an in vitro diagnostic device.

N/A

Intended Use / Indications for Use

THIS CONCENTRATE IS FORMULATED TO BE USED WITH A THREE STREAM HEMODIALYSIS MACHINE WHICH IS CALIBRATED FOR ACID AND BICARBONATE CONCENTRATES.

Product codes

78 KPO

Device Description

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Mentions image processing

Not Found

Mentions AI, DNN, or ML

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Input Imaging Modality

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Anatomical Site

Not Found

Indicated Patient Age Range

Not Found

Intended User / Care Setting

Not Found

Description of the training set, sample size, data source, and annotation protocol

Not Found

Description of the test set, sample size, data source, and annotation protocol

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Summary of Performance Studies

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Key Metrics

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Predicate Device(s)

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Reference Device(s)

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Predetermined Change Control Plan (PCCP) - All Relevant Information

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§ 876.5820 Hemodialysis system and accessories.

(a)
Identification. A hemodialysis system and accessories is a device that is used as an artificial kidney system for the treatment of patients with renal failure or toxemic conditions and that consists of an extracorporeal blood system, a conventional dialyzer, a dialysate delivery system, and accessories. Blood from a patient flows through the tubing of the extracorporeal blood system and accessories to the blood compartment of the dialyzer, then returns through further tubing of the extracorporeal blood system to the patient. The dialyzer has two compartments that are separated by a semipermeable membrane. While the blood is in the blood compartment, undesirable substances in the blood pass through the semipermeable membrane into the dialysate in the dialysate compartment. The dialysate delivery system controls and monitors the dialysate circulating through the dialysate compartment of the dialyzer.(1) The extracorporeal blood system and accessories consists of tubing, pumps, pressure monitors, air foam or bubble detectors, and alarms to keep blood moving safely from the blood access device and accessories for hemodialysis (§ 876.5540) to the blood compartment of the dialyzer and back to the patient.
(2) The conventional dialyzer allows a transfer of water and solutes between the blood and the dialysate through the semipermeable membrane. The semipermeable membrane of the conventional dialyzer has a sufficiently low permeability to water that an ultrafiltration controller is not required to prevent excessive loss of water from the patient's blood. This conventional dialyzer does not include hemodialyzers with the disposable inserts (Kiil type) (§ 876.5830) or dialyzers of high permeability (§ 876.5860).
(3) The dialysate delivery system consists of mechanisms that monitor and control the temperature, conductivity, flow rate, and pressure of the dialysate and circulates dialysate through the dialysate compartment of the dialyzer. The dialysate delivery system includes the dialysate concentrate for hemodialysis (liquid or powder) and alarms to indicate abnormal dialysate conditions. This dialysate delivery system does not include the sorbent regenerated dialysate delivery system for hemodialysis (§ 876.5600), the dialysate delivery system of the peritoneal dialysis system and accessories (§ 876.5630), or the controlled dialysate delivery system of the high permeability hemodialysis system § 876.5860).
(4) Remote accessories to the hemodialysis system include the unpowered dialysis chair without a scale, the powered dialysis chair without a scale, the dialyzer holder set, dialysis tie gun and ties, and hemodialysis start/stop tray.
(b)
Classification. (1) Class II (performance standards) for hemodialysis systems and all accessories directly associated with the extracorporeal blood system and the dialysate delivery system.(2) Class I for other accessories of the hemodialysis system remote from the extracorporeal blood system and the dialysate delivery system, such as the unpowered dialysis chair, hemodialysis start/stop tray, dialyzer holder set, and dialysis tie gun and ties. The devices subject to this paragraph (b)(2) are exempt from the premarket notification procedures in subpart E of part 807 of this chapter subject to the limitations in § 876.9.

0

Image /page/0/Picture/0 description: The image shows a logo for the Department of Health. The logo consists of a stylized, abstract symbol that resembles a series of curved lines or waves. The text "DEPARTMENT OF HEALTH" is arranged vertically along the left side of the symbol, with the letters oriented to be read from top to bottom.

Fublic Health Service

Food and Drug Administration 9200 Corporate Boulevard Rockville MD 2085C

MAY 2 6 1998

Mr. William J. Griswold, Jr. Solution Technology 4825 South 850 East South Ogden, Utah 84403

Re: K981043 Dialysol, Granusol, Renalsol and Biosol Liquid and Powder Dialysate Concentrate Dated: March 18, 1998 Received: March 20, 1998 Regulatory Class: II 21 CFR §876.5820/Product code: 78 KPO

Dear Mr. Griswold:

We have reviewed your Section 510/k) notification of intent to market the device referenced above and we have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class III (Premarket Approval), it may be subject to such additional controls. Existing major regulations affecting your device can be found in the Code of Feleral Resulations, Title 21, Parts 800 to 895. A substantially equivalent determination assumes compliance with the Current Good Manufacturing Practice requirements, as set forth in the Quality System Regulation (QS) for Medical Devices: General regulation (21 CFR Part 820) and that, through periodic QS inspections, the Food and Drug Administration (FDA) will verify such assumptions. Failure to comply with the GMP regulation may result in regulatory action. In addition, FDA may publish further announcements concerning your device in the Federal Register. Please note; this resonse to your premarket notification submission does not affect any obligation you might have under sections 542 of the Act for devices under the Electronic Product Radiation Control provisions, or other Federal laws or regulations.

This letter will allow you to begin marketing your device as described in your 510(k) premarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus, permits your device to proceed to the market.

If you desire specific advice for your device on our labeling regulation (2) CFR Part 801 and additionally 809.10 for in vitro diagnostic devices), please contact the Office of Compliance at (301) 594-4613. Additionally, for questions on the promotion and advertising of your device, please contact the Office of Compliance at (301) 594-4639. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21 CFR 807.97). Other general information on your responsibilities under the Act may be obtained from the Division of Small Manufacturers Assistance at its toll-free number (800) 638-2041 or (301) 443-6597 or at its Internet address "http://www.fda.gov/cdrh/dsmaln.html".

Sincerely yours.

Lillian Yin, Ph.D.

Director, Division of Reproductive, Abdominal, Ear, Nose and Throat and Radiological Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

1

510(k) Number (if known):_____________________________________________________________________________________________________________________________________________________

Device Name: DIALYSATE ACID CONCENTRATE (LIQUID & Powere)

Indications For Use:

THIS CONCENTRATE IS FORMILIATED TO BE USED WITH A THREE STREAM HEMODIALYSIS MACHING WHICH IS CALIBEATED FOR ACID AND BICARBONATE CONCENTRATES.

(PLEASE DO NOT WRITE BELOW THIS LINE - CONTINUE ON ANOTHER PAGE IF NEEDED)

Concurrence of CDRH, Office of Device Evaluation (ODE)

Robert D. Netheny/

(Division Sign-Off) Division of Reproductive, Abdominal, ENT, and Radiological Devices

510(k) Number K981047

Description Use
(Per 21 CFR 801.109)

OR

Over-The-Counter Use

(Optional Format 1-2-96)

2

310(k) Number (if known): ____________________________________________________________________________________________________________________________________________________

Device Name: DIALYSATE ACETATE CONCENTRATE (LIQUID & POWDER) Indications For Use:

THIS CONCENTRATE IS FORMULATED TO BE USED WITH A TWO STEEAM HEMODIAYSIS MACHINE CALIBRATEN TO AN ACETATE CONCENTRATED DICUTION RATIO OF 1:34

(PLEASE DO NOT WRITE BELOW THIS LINE - CONTINUE ON ANOTHER PAGE IF NEEDED)

Concurrence of CDRH, Office of Device Evaluation (ODE)

Robert R.Stling
(Division Sign-Off)
Division of Reproductive, Abdominal, ENT,
and Radiological Devices
510(k) Number K981043

. )scription Use
(Per 21 CFR 801.109)

OR

Over-The-Counter Use

(Optional Format 1-2-96)

3

K981043 ﮈ10(k) Number (if known): ________

Device Name: DIALYSATE BICARBONATE CONCENTRATE ( LIQUID & POWIDER)

Indications For Use:

THIS CONCENTRATE IS FORMULATED TO BE USED WITH A THEEE STREAM HEMODIALYSIS MACHINE WHICH 18 CALIBRATED FOR ACID AND BICARBONATE CONCENTRATES.

(PLEASE DO NOT WRITE BELOW THIS LINE - CONTINUE ON ANOTHER PAGE IF NEEDED)

Concurrence of CDRH, Office of Device Evaluation (ODE)

Robert R. Sither/

(Division Sign-Off) Division of Reproductive, Abdominal, ENT, and Radiological Devices 510(k) Number (98104 7

Prescription Use
(Per 21 CFR 801.109)

OR

Over-The-Counter Use

(Optional Format 1-2-96)