K Number
K971392
Device Name
HISTOFREEZER VERRUCA PLANA
Date Cleared
1997-10-21

(189 days)

Product Code
Regulation Number
878.4350
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP Authorized
Intended Use
Histofreezer is indicated for use in the treatment of the following: Genital Warts Molluscum Contagiosum Seborrhoeic Keratosis Skin Tags Verruca Plantaris Verruca Vulgaris Verruca Plana
Device Description
Not Found
More Information

Not Found

Not Found

No
The summary describes a device for treating skin conditions, and there is no mention of AI, ML, image processing, or any other technology typically associated with AI/ML in medical devices.

Yes
The device is indicated for use in the treatment of various medical conditions, such as Genital Warts and Molluscum Contagiosum, which directly relates to therapy.

No
Explanation: The device is indicated for treatment of various skin conditions, not for diagnosis.

No

The provided 510(k) summary describes a device called "Histofreezer" indicated for treating various skin conditions. The indications for use strongly suggest a physical treatment method (like cryotherapy, which is a common use for "Histofreezer" products), not a software-only diagnostic or therapeutic tool. The lack of any mention of software, image processing, AI, or data analysis further supports this conclusion.

Based on the provided information, Histofreezer is NOT an IVD (In Vitro Diagnostic) device.

Here's why:

  • Intended Use: The intended use describes the treatment of various skin conditions (warts, molluscum contagiosum, etc.). This is a therapeutic use, not a diagnostic one.
  • Lack of Diagnostic Information: The description does not mention any process of analyzing samples (like blood, tissue, or urine) to diagnose a disease or condition.
  • Device Description (Not Found): While the description is missing, the intended use is the primary indicator of whether a device is an IVD.

IVD devices are used to examine specimens from the human body to provide information for the diagnosis, monitoring, or treatment of a disease or condition. Histofreezer's purpose is to treat the conditions directly, not to diagnose them.

N/A

Intended Use / Indications for Use

Histofreezer is indicated for use in the treatment of the following:

Genital Warts
Molluscum Contagiosum
Seborrhoeic Keratosis
Skin Tags
Verruca Plantaris
Verruca Vulgaris
Verruca Plana

Product codes

GEH

Device Description

Not Found

Mentions image processing

Not Found

Mentions AI, DNN, or ML

Not Found

Input Imaging Modality

Not Found

Anatomical Site

Not Found

Indicated Patient Age Range

Not Found

Intended User / Care Setting

Not Found

Description of the training set, sample size, data source, and annotation protocol

Not Found

Description of the test set, sample size, data source, and annotation protocol

Not Found

Summary of Performance Studies

Not Found

Key Metrics

Not Found

Predicate Device(s)

Not Found

Reference Device(s)

Not Found

Predetermined Change Control Plan (PCCP) - All Relevant Information

Not Found

§ 878.4350 Cryosurgical unit and accessories.

(a)
Identification —(1)Cryosurgical unit with a liquid nitrogen cooled cryoprobe and accessories. A cryosurgical unit with a liquid nitrogen cooled cryoprobe and accessories is a device intended to destroy tissue during surgical procedures by applying extreme cold.(2)
Cryosurgical unit with a nitrous oxide cooled cryoprobe and accessories. A cryosurgical unit with a nitrous oxide cooled cryoprobe and accessories is a device intended to destroy tissue during surgical procedures, including urological applications, by applying extreme cold.(3)
Cryosurgical unit with a carbon dioxide cooled cryoprobe or a carbon dioxide dry ice applicator and accessories. A cryosurgical unit with a carbon dioxide cooled cryoprobe or a carbon dioxide dry ice applicator and accessories is a device intended to destroy tissue during surgical procedures by applying extreme cold. The device is intended to treat disease conditions such as tumors, skin cancers, acne scars, or hemangiomas (benign tumors consisting of newly formed blood vessels) and various benign or malignant gynecological conditions affecting vulvar, vaginal, or cervical tissue. The device is not intended for urological applications.(b)
Classification. Class II.

0

Image /page/0/Picture/1 description: The image contains the text 'Public Health Service'. The text is in a simple, sans-serif font and is horizontally aligned. The words are stacked on top of each other.

Food and Drug Administration 9200 Corporate Boulevard Rockville MD 20856

R. Sam Niedbala, Ph.D., BCFE .Executive Vice President STC Technologies, Inc. 1745 Eaton Avenue Bethlehem, Pennsylvania 18018-1799

OCT 21 1997

Re: K971392 Trade Name: Histofreezer® Verruca Plana Regulatory Class: II Product Code: GEH Dated: September 15, 1997 Received: September 16, 1997

Dear Dr. Niedbala:

We have reviewed your Section 510(k) notification of intent to market the device referenced above and we have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class II (Special Controls) or class III (Premarket Approval), it may be subject to such additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 895. A substantially equivalent determination assumes compliance with the current Good Manufacturing Practice requirements , as set forth in the Quality System Regulation (QS) for Medical Devices: General regulation (21 CFR Part 820) and that, through periodic (QS) inspections, the Food and Drug Administration (FDA) will verify such assumptions. Failure to comply with the GMP regulation may result in regulatory action. In addition, FDA may publish further announcements concerning your device in the Federal Register. Please note: this response to your premarket notification submission does not affect any obligation you might have under sections 531 through 542 of the Act for devices under the Electronic Product Radiation Control provisions, or other Federal laws or regulations.

Image /page/0/Picture/9 description: The image is a black and white logo for the U.S. Department of Health and Human Services. The logo features a stylized design of an abstract human figure with three curved lines representing the head, body, and legs. The figure is enclosed within a circular border, with the text "DEPARTMENT OF HEALTH & HUMAN SERVICES USA" arranged around the perimeter of the circle.

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Page 2 - R. Sam Niedbala, Ph.D., BCFE

This letter will allow you to begin marketing your device as described in your 510(k) premarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus, permits your device to proceed to the market.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801 and additionally 809.10 for in vitro diagnostic devices), please contact the Office of Compliance at (301) 594-4595. Additionally, for questions on the promotion and advertising of your device, please contact the Office of Compliance at (301) 594-4639. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21 CFR 807.97). Other general information on your responsibilities under the Act may be obtained from the Division of Small Manufacturers Assistance at its toll-free number (800) 638-2041 or (301) 443-6597 or at its internet address "http://www.fda.gov/cdrh/dsmamain.html".

Sincerely yours,

Aisellfo

Celia M. Witten, Ph.D., M.D. Director Division of General and Restorative Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

2

STATEMENT OF INDICATIONS FOR USE

510(k) Number (if known):

Device Name: Histofreezer® Verruca Plana _____________________________________________________________________________________________________________________________________

Indications For Use: Histofreezer is indicated for use in the treatment of the following:

Genital Warts Molluscum Contagiosum Seborrhoeic Keratosis Skin Tags Verruca Plantaris Verruca Vulgaris Verruca Plana

(PLEASE DO NOT WRITE BELOW THIS LINE - CONTINUE ON ANOTHER PAGE IF NEEDED)

Concurrence of CDRH, Office of Device Evaluation (ODE)

colly

(Division) Sign-Off) Division of General Restorative Devices 510(k) Number

Prescription Use
(Per 21 CFR 801.109)

OR

Over-The-Counter Use _________________________________________________________________________________________________________________________________________________________

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