K Number
K962418
Device Name
UREA NITROGEN (BUN) LIQUI-UV
Manufacturer
Date Cleared
1996-12-26

(185 days)

Product Code
Regulation Number
862.1770
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdparty
Intended Use
The device is used for the kinetic quantitative determination of Urea Nitrogen (BUN) in serum.
Device Description
The device test kit is comprised of two reagents, BUN Buffer (R1) and BUN Enzyme (R2), and a standard, 30mg/dL. A working reagent is prepared by combining five parts BUN Buffer (R1) to one part BUN Enzyme (R2).
More Information

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No
The summary describes a chemical reagent test kit for determining Urea Nitrogen levels. There is no mention of AI, ML, image processing, or any computational analysis beyond standard kinetic measurements.

No
The device is used for the kinetic quantitative determination of Urea Nitrogen (BUN) in serum, which is a diagnostic function, not a therapeutic one. It measures a substance in the body rather than treating a condition.

Yes
The device is used for the kinetic quantitative determination of Urea Nitrogen (BUN) in serum, which is a diagnostic measurement.

No

The device description explicitly states it is a "test kit" comprised of "two reagents" and a "standard," which are physical components, not software.

Yes, this device is an IVD (In Vitro Diagnostic).

Here's why:

  • Intended Use: The intended use explicitly states "kinetic quantitative determination of Urea Nitrogen (BUN) in serum." This is a test performed on a biological sample (serum) outside of the body to provide information about a patient's health status. This is the core definition of an in vitro diagnostic.
  • Device Description: The device is a "test kit" comprised of reagents and a standard. These are components used to perform a diagnostic test on a sample.
  • Performance Studies: The description of performance studies (method comparison, precision, linearity, sensitivity, stability, interference) are typical studies performed to validate the performance of an IVD.
  • Reference Device: The mention of a "Reference Device" which is another BUN test kit further indicates that this device is intended for diagnostic testing.

Therefore, based on the provided information, this device clearly fits the definition of an In Vitro Diagnostic.

N/A

Intended Use / Indications for Use

The device is used for the kinetic quantitative determination of Urea Nitrogen (BUN) in serum.

Product codes

75CDQ

Device Description

The device test kit is comprised of two reagents, BUN Buffer (R1) and BUN Enzyme (R2), and a standard, 30mg/dL. A working reagent is prepared by combining five parts BUN Buffer (R1) to one part BUN Enzyme (R2).

Mentions image processing

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Mentions AI, DNN, or ML

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Input Imaging Modality

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Anatomical Site

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Indicated Patient Age Range

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Intended User / Care Setting

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Description of the training set, sample size, data source, and annotation protocol

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Description of the test set, sample size, data source, and annotation protocol

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Summary of Performance Studies

Substantial equivalency was demonstrated by method comparison. Correlation was performed between the two test kits with a correlation coefficient of 0.999 and a regression equation of y = 1.012x - 0.47. In addition, precision, linearity, sensitivity, stability and interference studies were performed on Stanbio Laboratory, Inc., version of Urea Nitrogen (BUN) Liqui-UV®, Catalog # 2020. Results of these tests were found to be acceptable

Key Metrics

Correlation coefficient of 0.999 and a regression equation of y = 1.012x - 0.47.

Predicate Device(s)

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Reference Device(s)

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Predetermined Change Control Plan (PCCP) - All Relevant Information

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§ 862.1770 Urea nitrogen test system.

(a)
Identification. A urea nitrogen test system is a device intended to measure urea nitrogen (an end-product of nitrogen metabolism) in whole blood, serum, plasma, and urine. Measurements obtained by this device are used in the diagnosis and treatment of certain renal and metabolic diseases.(b)
Classification. Class II.

0

DEC 26 1996

KGC2418

510(k) SUMMARY

Submitter's Name Kirk Johnson Stanbio Laboratory, Inc. 2930 East Houston Street San Antonio, TX 78202

Tel. (210) 222-2108 Fax (210) 227-6367

Prepared By Kirk Johnson June 18, 1996

Product Name Trade name-Urea Nitrogen (BUN) Liqui-UV® Common name-Urea Nitrogen (BUN) Classification name-Urease and Glutamic Dehydrogenase, Urea Nitrogen Class II, 75CDQ

7:14

Substantial Equivalence of Device This test is substantially equivalent to : Product Name: BUN, UV Urease/GLDH (Kinetic) Manufacturer Boehringer Mannheim

Description of Device

The device test kit is comprised of two reagents, BUN Buffer (R1) and BUN Enzyme (R2), and a standard, 30mg/dL. A working reagent is prepared by combining five parts BUN Buffer (R1) to one part BUN Enzyme (R2).

Intended Use of Device

The device is used for the kinetic quantitative determination of Urea Nitrogen (BUN) in serum.

Comparison of Devices Both Urea Nitrogen (BUN) methods measure kinetically the decrease in absorbance due to consumption and conversion of NADH to NAD.

Performance Data

Substantial equivalency was demonstrated by method comparison. Correlation was performed between the two test kits with a correlation coefficient of 0.999 and a regression equation of y = 1.012x - 0.47.

In addition, precision, linearity, sensitivity, stability and interference studies were performed on Stanbio Laboratory, Inc., version of Urea Nitrogen (BUN) Liqui-UV®, Catalog # 2020. Results of these tests were found to be acceptable