K Number
K961645
Device Name
MRS-2D
Date Cleared
1996-10-31

(185 days)

Product Code
Regulation Number
882.5050
Reference & Predicate Devices
Predicate For
N/A
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
Intended Use

BioLex is indicated for relaxation training using alpha EEG biofeedback. In the protocol for relaxation training, BioLex provides a visual and/or auditory signal that corresponds to the patient's increase in alpha activity as an indicator of achieving a state of relaxation.

Device Description

The NRS-2D is a two channel electrophysiological signal acquisition and biofeedback device. The product is designed for use with a standard IBM PC/AT compatible computer and associated peripheral equipment. When assembled with the computer, the NRS-2D system will acquire EEG and biofeedback data, perform signal spectral analysis and quantification and provide auditory and/or visual feedback. At the user's discretion the NRS-2D can be factory configured as a single channel device.

AI/ML Overview

The provided text describes the Lexicor NRS-2D, a two-channel electrophysiological signal acquisition and biofeedback device. It focuses on device specifications and intended use but does not contain information about acceptance criteria or specific studies proving the device meets acceptance criteria.

Therefore, I cannot provide the requested information from the given text.

The document primarily covers:

  • Device Description: The NRS-2D is a two-channel device for acquiring EEG and biofeedback data, performing signal spectral analysis, and providing auditory/visual feedback. It can also be configured as a single-channel device.
  • Intended Use: For relaxation training using alpha EEG biofeedback, providing visual and/or auditory signals corresponding to increased alpha activity.
  • Warnings and Contraindications: Patients unwilling or unable to understand feedback principles, those experiencing anxiety from EEG biofeedback, and a warning regarding potential causal relationship between EEG training and seizures in epilepsy.
  • Technological Characteristics: Details about the acquisition and preprocessing unit, including filters (lowpass, highpass, notch), A/D converter, microprocessor control, and communication with a PC. Specifications like sampling rate (128Hz), gain (8,000), and electrode continuity checking are mentioned.
  • Device Specifications Table: A table outlining physical dimensions, signal acquisition parameters (channels, sampling rate, frequency resolution, noise, notch filtering, CMRR, gain, filters, input impedance, A/D resolution), and power details (AC power, battery power).

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NRS-2D 510(k) Notification

510(k) Summary Lexicor NRS-2D Date Prepared: 4/16/96

K961645

OCT 3 1 1996

TABLE OF CONTENTS

TABLE OF CONTENTS6-2
SUBMITTER6-2
CONTACT PERSON6-2
DEVICE NAME6-2
DEVICE DESCRIPTION6-3
INTENDED USE6-3
PREDICATE DEVICE6-4
SUMMARY OF TECHNOLOGICAL CHARACTERISTICS6-4

SUBMITTER

Lexicor Medical Technology, Inc. 5589 Arapahoe Ave. #206 Boulder, CO 80303 Telephone: 303.443.9944

FAX: 303.443.0591

CONTACT PERSON

Michael M. Shupe Quality and Regulatory Affairs Manager

DEVICE NAME

.

  • . Proprietary Name: NRS-2D
    • Common Name: Electroencephalograph with an electroencephalogram signal spectrum analyzer and biofeedback options.
  • . Classification Names: Electroencephalograph

Analyzer, Spectrum, Electroencephalogram Signal

Device, Biofeedback

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NRS-2D 510(k) Notification

Section 6

510(k) Summary Lexicor NRS-2D Date Prepared: 4/16/96 Revised: 7/29/96

DEVICE DESCRIPTION

The NRS-2D is a two channel electrophysiological signal acquisition and biofeedback device. The product is designed for use with a standard IBM PC/AT compatible computer and associated peripheral equipment. When assembled with the computer, the NRS-2D system will acquire EEG and biofeedback data, perform signal spectral analysis and quantification and provide auditory and/or visual feedback. At the user's discretion the NRS-2D can be factory configured as a single channel device.

INTENDED USE

The NRS-2D uses Lexicor's BioLex software to perform its intended use.

BioLex Software

Description

BioLex provides visual and/or auditory feedback based on parameters derived from spectral analysis of the electroencephalogram (EEG) signal.

Indications

BioLex is indicated for relaxation training using alpha EEG biofeedback. In the protocol for relaxation training, BioLex provides a visual and/or auditory signal that corresponds to the patient's increase in alpha activity as an indicator of achieving a state of relaxation.

Warnings and Contraindications

BioLex is contraindicated in patients with the following conditions:

    1. Individuals who are unwilling or unable to understand the general principles and goals of the feedback used. This includes individuals with excessive behavioral problems or low IQ.
    1. Individuals who experience anxiety or an unpleasant experience associated with EEG biofeedback training.

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510(k) Summary Lexicor NRS-2D Date Prepared: 4/16/96

    1. In epilepsy, there may be a causal relationship between EEG training of certain EEG frequencies and incidence of seizure.
      Certain patients may be unable to learn to control the EEG through biofeedback. Therapy should be discontinued if periodic monitoring of therapeutic progress indicates that the patient is not learning despite adequate review of instructions for feedback.

Side Effects

There have been clinical reports of dizziness, drowsiness, fatigue and anxiety associated with feedback employing alpha enhancement.

Frequency and Duration of Treatment

Duration of treatment ranges from 1 to 30 sessions and frequency from 1 to 7 times weekly depending on the needs of the patient.

Operation and Usage

Please refer to the Biolex Software Manual for complete operating instructions prior to use.

PREDICATE DEVICE

Lexicor NRS-4, 510(k) K920038

SUMMARY OF TECHNOLOGICAL CHARACTERISTICS

System Block Diagram

Image /page/2/Figure/15 description: The image shows a block diagram of a system. The system consists of five blocks: Patient Interface Cable, Acquisition and Preprocessing Unit, Computer Interface Cable, and Personal Computer. Arrows connect the blocks in a sequential manner, indicating the flow of data or signals through the system.

A simple software command will allow the user to check all electrode contacts at any time, while the patient is connected to the NRS-2D without having to disconnect the electrodes from the NRS-2D and check the electrode/skin contact with a separate impedance meter.

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510(k) Summary Lexicor NRS-2D Date Prepared: 4/16/96

Patient Interface

When EEG electrodes are used and applied properly, contact impedances below Sk-10k Ohms can be obtained.

Acquisition and Preprocessing Unit

The acquisition and preprocessing unit is a self-contained electrically isolated module which amplifies and filters the subject's EEG signals and converts them from an analog to digital form.

Each of the NRS-2D's channels consists of a continuity checking circuit, followed by a preamplifier and then lowpass, highpass and notch filters.

The notch filter (60 Hz USA) attenuates electrical mains interference noise entering the signal path.

Finally the channels are scanned by a 12 bit combination multiplexer and Analog to Digital converter with Sample and Hold.

A microprocessor in the NRS-2D controls the continuity checking and A/D conversion process, transmits data to, and receives commands from the PC through on-board optical isolators. Communication with the PC is accomplished via a 25 conductor cable which connects to the NRS-2D back panel's DB-25 connector and to any PC parallel printer port.

A binary executable code for the microprocessor handles the communication between the Acquisition and the host software application (BioLex and NeuroLex). The code instructs the card to reset the input multiplexer, read the data into an area of dual-ported memory in the processor and set interrupt vector 7 of the host PC interrupt system. The host software's interrupt routine then reads the data form the processor memory into computer RAM. This process is repeated for each set of input samples of the digitized EEG.

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510(k) Summary Lexicor NRS-2D Date Prepared: 4/16/96

Image /page/4/Figure/3 description: This image shows a block diagram of a system. The system starts with a "Continuity Checking" block, which receives input from a patient. The signal then passes through a "Pre-Amp", "Low Pass Filter", "High Pass Filter", and "Optical Interface" in sequence. The signal is then fed into a "Microprocessor" after passing through a "Notch Filter" and "A/D Converter". The microprocessor also handles communication to and from a computer.

NRS-2D Functional Block Diagram

The NRS-2D has a fixed sampling rate of 128Hz, a fixed gain of 8,000 and a built in electrode continuity checking capability.

A simple software command will allow the user to check all electrode contacts at any time, while the patient is connected to the NRS-2D without having to disconnect the electrodes from the NRS-2D and check the electrode/skin contact with a separate impedance meter.

Power

The NRS-2D uses a medical grade single output switching power supply with the following features:

Universal input from 90-264VAC

Power on LED

Overvoltage and short circuit protection Built-in EMI filter-class B

UL-544, CSA-223 and TUV-601 Safety approvals

Output-12 VDC, 2A

A 9.6 VDC rechargeable battery pack is available as an option.

:

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NRS-2D 510(k) Notification

Section 6

510(k) Summary Lexicor NRS-2D Date Prepared: 4/16/96 Revised: 7/29/96

The following is a table of the NRS-2D specifications.

PhysicalDimensions6" (l) x 3" (w) x1.125" (h)AC Power
Signal AcquisitionVoltage100/240 volts, 30 watts, 50/60 Hz
Channels1 or 2Current< 1 amp
Sampling Rate128HzLeakage Current< 20μA
FrequencyResolution0.5 HzFuses0.8 amp, 250 volt
Noise< 2μV pp @ 0.5-32 HzBattery Power
Notch Filtering60 or 50 HzVoltage9.6 volts
Common ModeRejection Ratio> 90 db at 60 HzCurrent600 MAH
Gain8kTypeRechargeable
Artifact Rejectionmanual/automaticControl Software
Low Pass Filters32 HzBioLex
High Pass Filters0.5 Hz
Input Impedance>1 GΩ
A/D Resolution12 bits

, " " "

§ 882.5050 Biofeedback device.

(a)
Identification. A biofeedback device is an instrument that provides a visual or auditory signal corresponding to the status of one or more of a patient's physiological parameters (e.g., brain alpha wave activity, muscle activity, skin temperature, etc.) so that the patient can control voluntarily these physiological parameters.(b)
Classification. Class II (special controls). The device is exempt from the premarket notification procedures in subpart E of part 807 of this chapter when it is a prescription battery powered device that is indicated for relaxation training and muscle reeducation and prescription use, subject to § 882.9.