K Number
K143598
Device Name
Lapro-Clip Auto Suture Reusable Long Clip Applier
Manufacturer
Date Cleared
2015-03-12

(84 days)

Product Code
Regulation Number
878.4300
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdparty
Intended Use
Lapro-Clip™ absorbable ligating clip cartridges are intended for use as absorbable ligatures. Lapro-Clip™ absorbable ligating clip cartridges are radio transparent and will not interfere with interpretations of postoperative X-ray, CT, or MRI scans. The Lapro-Clip™ absorbable ligating clip cartridge may be used for ligation of the cystic duct and other general ligation.
Device Description
The Lapro-Clip™ absorbable ligating clip is delivered by a single use cartridge and actuated by a reusable applier. Lapro-Clip™ absorbable ligating clip cartridges are molded from two polymers: polyglycolic acid and polyglyconate. The outer body is polyglycolic acid and slides over a polyglyconate inner track. Lapro-Clip™ absorbable ligating clips are supplied sterile and undyed. Lapro-Clip™ absorbable ligating clip cartridges are available in two sizes, Medium/Large and Large. Clips are supplied one clip per single use cartridge with either one, two, or six cartridges per sterile package. The Lapro-Clip™ reusable clip appliers are available in three sizes: The Lapro-Clip™ short reusable clip applier is 11cm in length with a shaft diameter of 10mm. The Lapro-Clip™ standard reusable clip applier is 26.5cm in length with a shaft diameter of 10mm. The Lapro-Clip™ long reusable clip applier is 33cm in length with a shaft diameter of 10mm.
More Information

No
The device description and performance studies focus on the mechanical properties and function of a physical ligating clip and applier, with no mention of software, algorithms, or data processing that would indicate AI/ML.

Yes
The device is intended for "ligation of the cystic duct and other general ligation," indicating its use in a medical procedure to tie off blood vessels or ducts, which is a therapeutic intervention.

No
The device is described as an absorbable ligating clip used for general ligation, such as of the cystic duct. Its purpose is to physically ligate or tie off structures, not to diagnose conditions or diseases.

No

The device description clearly details physical components made of polymers and metal (applier), indicating it is a hardware device, not software-only.

Based on the provided information, this device is not an IVD (In Vitro Diagnostic).

Here's why:

  • Intended Use: The intended use is for "absorbable ligatures" and "ligation of the cystic duct and other general ligation." This describes a surgical procedure performed on the body, not a test performed on a sample taken from the body.
  • Device Description: The device is a "ligating clip" and "applier." This is a surgical tool used to physically close off vessels or tissues.
  • Lack of IVD Characteristics: There is no mention of analyzing biological samples (blood, urine, tissue, etc.), detecting specific analytes, or providing diagnostic information based on laboratory testing.

IVD devices are used to examine specimens derived from the human body to provide information for diagnostic, monitoring, or compatibility purposes. This device is a surgical instrument used for physical ligation during a procedure.

N/A

Intended Use / Indications for Use

Lapro-Clip™ absorbable ligating clip cartridges are intended for use as absorbable ligatures. Lapro-Clip™ absorbable ligating clip cartridges are radio transparent and will not interfere with interpretations of postoperative X-ray, CT, or MRI scans. The Lapro-Clip™ absorbable ligating clip cartridge may be used for ligation of the cystic duct and other general ligation.

Product codes

FZP,GDO

Device Description

The Lapro-Clip™ absorbable ligating clip is delivered by a single use cartridge and actuated by a reusable applier.
Lapro-Clip™ absorbable ligating clip cartridges are molded from two polymers: polyglycolic acid and polyglyconate. The outer body is polyglycolic acid and slides over a polyglyconate inner track. Lapro-Clip™ absorbable ligating clips are supplied sterile and undyed.
Lapro-Clip™ absorbable ligating clip cartridges are available in two sizes, Medium/Large and Large. Clips are supplied one clip per single use cartridge with either one, two, or six cartridges per sterile package. The Lapro-Clip™ reusable clip appliers are available in three sizes: The Lapro-Clip™ short reusable clip applier is 11cm in length with a shaft diameter of 10mm. The Lapro-Clip™ standard reusable clip applier is 26.5cm in length with a shaft diameter of 10mm. The Lapro-Clip™ long reusable clip applier is 33cm in length with a shaft diameter of 10mm.

Mentions image processing

Not Found

Mentions AI, DNN, or ML

Not Found

Input Imaging Modality

Not Found

Anatomical Site

cystic duct

Indicated Patient Age Range

Not Found

Intended User / Care Setting

Not Found

Description of the training set, sample size, data source, and annotation protocol

Not Found

Description of the test set, sample size, data source, and annotation protocol

Not Found

Summary of Performance Studies

Performance studies were conducted to demonstrate that the proposed device, the Lapro-Clip™ Auto Suture™ Reusable Long Clip Applier is substantially equivalent to the predicate device. In-vitro testing that supports the intended use of this device includes:
In-vitro Testing:

  • Visual Examination
  • Firing Force
  • Cartridge Latch Depression
  • Trigger Return Force
  • General Safety and Efficacy
  • Leak Resistance
  • Barrel Rotation Torque
  • Clip Formation/Deployment
  • Lifecycle reliability test

Key Metrics

Not Found

Predicate Device(s)

K925602

Reference Device(s)

Not Found

Predetermined Change Control Plan (PCCP) - All Relevant Information

Not Found

§ 878.4300 Implantable clip.

(a)
Identification. An implantable clip is a clip-like device intended to connect internal tissues to aid healing. It is not absorbable.(b)
Classification. Class II.

0

Image /page/0/Picture/1 description: The image shows the seal of the Department of Health & Human Services - USA. The seal is circular and contains the words "DEPARTMENT OF HEALTH & HUMAN SERVICES - USA" around the perimeter. In the center of the seal is an abstract image of a human face in profile, with three overlapping profiles creating a sense of depth.

Food and Drug Administration 10903 New Hampshire Avenue Document Control Center - WO66-G609 Silver Spring, MD 20993-0002

March 12, 2015

Covidien LLC Ms. Rebecca Magnanimo Regulatory Affairs Product Specialist 60 Middletown Avenue North Haven, Connecticut 06473

Re: K143598

Trade/Device Name: Lapro-Clip" Auto Suture™ Reusable Long Clip Applier Regulation Number: 21 CFR 878.4300 Regulation Name: Implantable Clip Regulatory Class: Class II Product Code: FZP Dated: February 10, 2015 Received: February 12, 2015

Dear Ms. Magnanimo:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration. Please note: CDRH does not evaluate information related to contract liability warranties. We remind you; however, that device labeling must be truthful and not misleading.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); medical device reporting (reporting of medical

1

device-related adverse events) (21 CFR 803); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please contact the Division of Industry and Consumer Education at its toll-free number (800) 638-2041 or (301) 796-7100 or at its Internet address

http://www.fda.gov/MedicalDevices/Resourcesfor You/Industry/default.htm. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). For questions regarding the reporting of adverse events under the MDR regulation (21 CFR Part 803), please go to

http://www.fda.gov/MedicalDevices/Safety/ReportaProblem/default.htm for the CDRH's Office of Surveillance and Biometrics/Division of Postmarket Surveillance.

You may obtain other general information on your responsibilities under the Act from the Division of Industry and Consumer Education at its toll-free number (800) 638-2041 or (301) 796-7100 or at its Internet address

http://www.fda.gov/MedicalDevices/ResourcesforYou/Industry/default.htm.

Sincerely yours,

David Krause -S

  • Binita S. Ashar, M.D., M.B.A., F.A.C.S. for Director Division of Surgical Devices Office of Device Evaluation Center for Devices and Radiological Health
    Enclosure

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Indications for Use

510(k) Number (if known) K143598

Device Name

Lapro-Clip™ Auto Suture™ Reusable Long Clip Applier

Indications for Use (Describe)

Lapro-Clip™ absorbable ligating clip cartridges are intended for use as absorbable ligatures. Lapro-Clip™ absorbable ligating clip cartridges are radio transparent and will not interfere with interpretations of postoperative X-ray, CT, or MRI scans. The Lapro-Clip™ absorbable ligating clip cartridge may be used for ligation of the cystic duct and other general ligation.

Type of Use (Select one or both, as applicable)

2 Prescription Use (Part 21 CFR 801 Subpart D)

Over-The-Counter Use (21 CFR 801 Subpart C)

PLEASE DO NOT WRITE BELOW THIS LINE - CONTINUE ON A SEPARATE PAGE IF NEEDED.

FOR FDA USE ONLY

Concurrence of Center for Devices and Radiological Health (CDRH) (Signature)

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510(k) Summary

| SUBMITTER: | Covidien IIc
60 Middletown Avenue
North Haven, CT 06473 USA |
|-------------------------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
| CONTACT PERSON: | Rebecca Magnanimo
Regulatory Affairs Product Specialist
Covidien IIc
Phone: (203) 492-6479
Fax: (203) 492-5029
e-mail: Rebecca.magnanimo@covidien.com |
| DATE PREPARED: | 12/17/14 |
| PRODUCT CODE: | GDO |
| REGULATION NUMBER: | 21 CFR 878.4800 |
| TRADE/PROPRIETARY NAME: | Lapro-Clip™ Auto Suture™ Reusable Long Clip Applier |
| COMMON/USUAL NAME: | Absorbable Clip Applier |
| CLASSIFICATION NAME: | Laparoscope, General & Plastic Surgery |
| PREDICATE DEVICES: | Lapro-Clip™ Auto Suture™ Reusable Standard and
Short Clip Applier (K925602) |
| DEVICE DESCRIPTION: | The Lapro-Clip™ absorbable ligating clip is delivered by
a single use cartridge and actuated by a reusable
applier.
Lapro-Clip™ absorbable ligating clip cartridges are
molded from two polymers: polyglycolic acid and
polyglyconate. The outer body is polyglycolic acid and
slides over a polyglyconate inner track. Lapro-Clip™
absorbable ligating clips are supplied sterile and undyed.
Lapro-Clip™ absorbable ligating clip cartridges are
available in two sizes, Medium/Large and Large. Clips
are supplied one clip per single use cartridge with either
one, two, or six cartridges per sterile package. The
Lapro-Clip™ reusable clip appliers are available in three
sizes: The Lapro-Clip™ short reusable clip applier is
11cm in length with a shaft diameter of 10mm. The
Lapro-Clip™ standard reusable clip applier is 26.5cm in
length with a shaft diameter of 10mm. The Lapro-Clip™
long reusable clip applier is 33cm in length with a shaft
diameter of 10mm. |

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INTENDED USE

Lapro-Clip™ absorbable ligating clip cartridges are intended for use as absorbable ligatures. Lapro-Clip™ absorbable ligating clip cartridges are radiotransparent and will not interfere with interpretations of postoperative X-ray, CT, or MRI scans. The Lapro-Clip™ absorbable ligating clip cartridge may be used for liqation of the cystic artery and cystic duct and other qeneral liqation.

SUMMARY COMPARING THE TECHNOLOGICAL CHARACTERISTICS OF THE SUBJECT AND PREDICATE DEVICES:

The proposed Lapro-Clip™ Auto Suture™ Reusable Long Clip Applier manufactured with a longer shaft length and tested to update sterilization, cleaning and lifecycle testing to current FDA Draft Guidance for "Processing/Reprocessing Medical Devices in Health Care Settings" is equivalent to Lapro-Clip™ Auto Suture™ Reusable Standard and Short Clip Applier (K925602) in terms of the following technological characteristics:

  • Indication ।
  • Raw materials ।
  • Performance characteristics -
  • -Biocompatibility
  • -Stability
  • Life Cycle Reliability -

Biocompatibility studies were conducted on existing Lapro-Clip™ Auto Suture™ Reusable Standard and Short Clip Applier (K925602). The proposed device contains same materials as predicate.

Sterilization and cleaning studies for the proposed Lapro-Clip™ Auto Suture™ Reusable Long Clip Applier and predicate device Lapro-Clip™ Auto Suture™ Reusable Standard and Short Clip Applier (K925602) have been performed.

Performance studies were conducted to demonstrate that the proposed device, the Lapro-Clip™ Auto Suture™ Reusable Long Clip Applier is substantially equivalent to the predicate device. In-vitro testing that supports the intended use of this device includes:

In-vitro Testina:

  • Visual Examination .
  • Firing Force
  • 트 Cartridge Latch Depression
  • Trigger Return Force ■
  • . General Safety and Efficacy

5

  • Leak Resistance
  • Barrel Rotation Torque
  • Clip Formation/Deployment
  • = Lifecycle reliability test

In-vivo testing was not performed for this change. The clip cartridge with clips is sold separately and was previously tested in original 510(k) for clip applier and clip cartridge (K925602). This modification had no impact to clip cartridge or clips.

CONCLUSION:

The results of testing demonstrate that the modified the Lapro-Clip™ Auto Suture™ Reusable Long Clip Applier is substantially equivalent to the legally marketed Lapro-Clip™ Auto Suture™ Reusable Clip Applier (K925602).