K Number
K102822
Date Cleared
2011-01-10

(104 days)

Product Code
Regulation Number
872.3640
Panel
Dental
Reference & Predicate Devices
Predicate For
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
Intended Use

The Implant-One™ system is indicated for surgical placement in partially or completely edentulous upper or lower jaws to provide a means for prosthetic attachment to restore a patient's chewing function. The Implant-One™ system is indicated for immediate loading only when primary stability is achieved and with the appropriate occlusal loading.

Device Description

The Implant-One™ Dental Implants include endosseous dental implants, cover screws, healing caps, dental implant abutments and abutment screws in a variety of sizes to accommodate differing patient anatomy. Endosseous implants are self-tapping, root-form and threaded. They range from 3.25mm to 5.5mm in diameter with lengths ranging from 8mm to 14mm and have an internal, threaded abutment connection having a Morse style taper. Cover screws and healing caps provide protection to the threads of the abutment connection during endosseous and gingival healing. Cover screws are pre-packaged with each implant. Healing caps are provided as an alternative to the cover screw and are packaged separately. Abutment options include Standard and Restorative in various heights. These are fastened to the implant using an abutment screw.

AI/ML Overview

The provided text describes the 510(k) summary for Custom Dental Implants Inc.'s Implant-One™ Dental Implants. This document focuses on demonstrating substantial equivalence to predicate devices through non-clinical testing rather than through clinical studies involving human patients or complex AI algorithms. Therefore, many of the requested elements for describing a study proving device acceptance (like sample sizes for test/training sets, expert qualifications, adjudication methods, MRMC studies, or specific ground truth types for AI models) are not applicable to this submission.

The acceptance criteria are implicitly defined by the demonstration of equivalent performance to predicate devices through mechanical testing.

Here's a breakdown based on the available information:

1. Table of Acceptance Criteria and Reported Device Performance

Note: The acceptance criteria for this device are not explicitly stated as quantitative thresholds in the document. Instead, the acceptance is based on demonstrating that the "worst case Implant-One™ system construct performed as well as or better than the predicate devices" in non-clinical dynamic testing according to ISO 14801.

Acceptance Criteria (Implicit)Reported Device Performance (Non-Clinical Dynamic Testing according to ISO 14801)
Mechanical performance for worst-case construct is equivalent to or better than predicate devices.The Implant-One™ system performed as well as or better than the predicate devices.

2. Sample size used for the test set and the data provenance

  • Sample Size: Not specified for non-clinical testing, however it refers to "worst case Implant-One™ system construct" which usually implies a limited number of samples designed to represent the most challenging scenario.
  • Data Provenance: Not applicable as it's a non-clinical mechanical test. The test was performed by Custom Dental Implants Inc.

3. Number of experts used to establish the ground truth for the test set and the qualifications of those experts

  • Not applicable as no human experts were involved in establishing ground truth for mechanical testing. The "ground truth" here is the objective measurement of mechanical properties.

4. Adjudication method for the test set

  • Not applicable as no adjudication was needed for objective mechanical testing.

5. If a multi reader multi case (MRMC) comparative effectiveness study was done, If so, what was the effect size of how much human readers improve with AI vs without AI assistance

  • Not applicable. This is a medical device (dental implant) 510(k) submission, not an AI/software as a medical device (SaMD) submission, and no MRMC study was performed.

6. If a standalone (i.e. algorithm only without human-in-the-loop performance) was done

  • Not applicable. This is a medical device (dental implant) 510(k) submission, not an AI/SaMD submission.

7. The type of ground truth used

  • Ground Truth Type: Objective mechanical measurements (e.g., fatigue life, fracture strength) as defined by the ISO 14801 standard for dynamic testing of endosseous dental implants. This is a physical, measurable "ground truth" for the device's performance under simulated physiological loading conditions.

8. The sample size for the training set

  • Not applicable. There was no training set as no machine learning or AI algorithm was developed or evaluated.

9. How the ground truth for the training set was established

  • Not applicable. There was no training set.

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K102822

Custom Dental Implants

Norwalk, WI 54648

JAN 1 0 2011

Image /page/0/Picture/4 description: The image shows the logo for Implant-One Dental Implants. The logo features a stylized image of a tooth on the left side. The text "Implant-One" is written in a bold, sans-serif font, with the words "Dental Implants" written in a smaller font below.

510(k) Summary

Date:20 December 2010
Sponsor:Custom Dental Implants Inc.18975 Incline RoadNorwalk, WI 54648Phone 608.269.3940
Contact Person:Thomas Arendt, Vice President
Proposed TradeName:Implant-One™ Dental Implants
Device ClassificationClass II
Classification Name:Endosseous dental implant & Endosseous dental implant abutment
Regulation:872.3640 & 872.3630
Device ProductCodes:DZE & NHA
Device Description:The Implant-One™ Dental Implants include endosseous dentalimplants, cover screws, healing caps, dental implant abutments andabutment screws in a variety of sizes to accommodate differingpatient anatomy. Endosseous implants are self-tapping, root-formand threaded. They range from 3.25mm to 5.5mm in diameter withlengths ranging from 8mm to 14mm and have an internal, threadedabutment connection having a Morse style taper. Cover screws andhealing caps provide protection to the threads of the abutmentconnection during endosseous and gingival healing. Cover screwsare pre-packaged with each implant. Healing caps are provided asan alternative to the cover screw and are packaged separately.Abutment options include Standard and Restorative in variousheights. These are fastened to the implant using an abutment screw.
Intended Use:The Implant-One™ system is indicated for surgical placement inpartially or completely edentulous upper or lower jaws to provide ameans for prosthetic attachment to restore a patient's chewingfunction. The Implant-One™ system is indicated for immediateloading only when primary stability is achieved and with theappropriate occlusal loading.
Materials:The Implant-One™ components are manufactured from titaniumalloy (Ti-6Al-4V) as described by ASTM F1472 or stainless steelaccording to ASTM A582.
Predicate Devices:Biomet 3i dental implants and abutments (K063341/K072642)Zimmer Screw Vent and Contour Abutment (K061410/K061847)FRIADENT Implant Systems (K073075)

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The fundamental scientific technology of the Implant-One™ system Technological is the same as previously cleared devices as shown below. Characteristics:

System:Implant-OneBiomet 3iZimmerAnkylos
Material ofmanufacture:Titanium and/or titanium alloy
Design:
Endosseous implantRoot-form,TaperedRoot-form,Straight andtaperedRoot-form,Straight andtaperedRoot-form,Straight
Method ofstabilizationThreaded fixationThreaded fixationThreaded fixationThreaded fixation
Range of Diameters3.25 - 5.5mm3.25 - 6mm3.3 - 6mm3.5 - 7.0mm
Range of Lengths8 - 14mm8.5 - 15mm8 - 16mm8 - 17mm
Modified surfaceYes, AlO2blastedYes, acid etchedYes,microtextured orHA coatedYes, grit blastedand etched
Connection toabutmentHex alignment,6° included taper,screw attachmentHex alignment,screw attachmentHex alignment,1° taper, screwattachmentKeyedalignment,friction-locktaper, threadattachment
AbutmentsStandard, Ball,Gold copingStandard, BallStandard, Ball,Gold copingStandard, Ball,Gold coping

Non-clinical dynamic testing of the worst case Implant-One™ system Performance Data: construct was performed according to ISO 14801. The mechanical test results demonstrated that the Implant-One™ system performs as well as or better than the predicate devices. No clinical data was used in support of this submission.

The Implant-One™ system is substantially equivalent to the Conclusion: predicate devices referenced above is therefore safe and effective for its intended use.

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Food and Drug Administration 10903 New Hampshire Avenue Document Control Room -WO66-G609 Silver Spring. MID 20993-0002

Custom Dental Implants, Incorporated C/O Ms. Karen E. Warden President BackRoads Consulting, Incorporated 8202 Sherman Road Chesterland, Ohio 44026

JAN 1 0 201

Re: K102822

Trade/Device Name: Implant-One" System Regulation Number: 21 CFR 872.3640 Regulation Name: Endosseous Dental Implant & Endosseous Dental Implant Abutment Regulatory Class: II Product Code: DZE & NHA Dated: December 21, 2010 Received: December 23, 2010

Dear Ms. Warden:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration. Please note: CDRH does not evaluate information related to contract liability warranties. We remind you, however, that device labeling must be truthful and not misleading.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

:

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Page 2- Ms. Warden

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements. including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); medical device reporting (reporting of medical device-related adverse events) (21 CFR 803); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the clectronic product radiation control provisions (Sections 531-542 of the Act): 21 CFR 1000-1050.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please go to

http://www.fda.gov/AboutFDA/CentersOffices/CDRH/CDRHOffices/ucm115809.htm for the Center for Devices and Radiological Health's (CDRH's) Office of Compliance. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). For questions regarding the reporting of adverse events under the MDR regulation (21 CFR Part 803), please go to

http://www.fda.gov/MedicalDevices/Safety/ReportaProblem/default.htm for the CDRH's Office of Surveillance and Biometrics/Division of Postmarket Surveillance.

You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers. International and Consumer Assistance at its toll-free number (800) 638-2041 or (301) 796-7100 or at its Internet address http://www.fda.gov/MedicalDevices/Resourcesfor You/Industry/default.htm.

Sincerely yours.

h for

Anthony D. Watson, B.S., M.S., M.B.A. Director Division of Anesthesiology, General Hospital, Infection Control and Dental Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

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Indications for Use Statement

4102822 510(k) Number:

Device Name: Implant-One™ System

Indications for Use:

The Implant-One™ system is indicated for surgical placement in partially or completely edentulous upper or lower jaws to provide a means for prosthetic attachment to restore a patient's chewing function. The Implant-One™ system is indicated for immediate loading only when primary stability is achieved and with the appropriate occlusal loading.

Prescription Use _____________________________________________________________________________________________________________________________________________________________

AND/OR

Over-the-Counter Use_

(21 CFR 801 Subpart D)

(21 CFR 807 Subpart C)

(PLEASE DO NOT WRITE BELOW THIS LINE - CONTINUE ON ANOTHER PAGE IF NEEDED)

Concurrence of CDRH, Office of Device Evaluation (ODE)

Simon Rogers

(Division Sign-Off) Division of Anesthesiology, General Hospital Infection Control, Dental Devices

510(k) Number: K102833

§ 872.3640 Endosseous dental implant.

(a)
Identification. An endosseous dental implant is a prescription device made of a material such as titanium or titanium alloy that is intended to be surgically placed in the bone of the upper or lower jaw arches to provide support for prosthetic devices, such as artificial teeth, in order to restore a patient's chewing function.(b)
Classification. (1) Class II (special controls). The device is classified as class II if it is a root-form endosseous dental implant. The root-form endosseous dental implant is characterized by four geometrically distinct types: Basket, screw, solid cylinder, and hollow cylinder. The guidance document entitled “Class II Special Controls Guidance Document: Root-Form Endosseous Dental Implants and Endosseous Dental Implant Abutments” will serve as the special control. (See § 872.1(e) for the availability of this guidance document.)(2)
Classification. Class II (special controls). The device is classified as class II if it is a blade-form endosseous dental implant. The special controls for this device are:(i) The design characteristics of the device must ensure that the geometry and material composition are consistent with the intended use;
(ii) Mechanical performance (fatigue) testing under simulated physiological conditions to demonstrate maximum load (endurance limit) when the device is subjected to compressive and shear loads;
(iii) Corrosion testing under simulated physiological conditions to demonstrate corrosion potential of each metal or alloy, couple potential for an assembled dissimilar metal implant system, and corrosion rate for an assembled dissimilar metal implant system;
(iv) The device must be demonstrated to be biocompatible;
(v) Sterility testing must demonstrate the sterility of the device;
(vi) Performance testing to evaluate the compatibility of the device in a magnetic resonance (MR) environment;
(vii) Labeling must include a clear description of the technological features, how the device should be used in patients, detailed surgical protocol and restoration procedures, relevant precautions and warnings based on the clinical use of the device, and qualifications and training requirements for device users including technicians and clinicians;
(viii) Patient labeling must contain a description of how the device works, how the device is placed, how the patient needs to care for the implant, possible adverse events and how to report any complications; and
(ix) Documented clinical experience must demonstrate safe and effective use and capture any adverse events observed during clinical use.