K Number
K091696
Device Name
SAVI WIRELESS, MODEL PM500
Manufacturer
Date Cleared
2009-10-26

(138 days)

Product Code
Regulation Number
870.2910
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP Authorized
Intended Use
The SAVI Wireless PM500, is a pager-sized, handheld or patient worn device designed specifically to record and transmit ambulatory ECG signals. The device can be worn for days or weeks, as it is intended for use by patients who are experiencing symptoms that are transient and infrequent in nature.
Device Description
The SAVI Wireless Model PM500, is a small, auto triggered, hand-held device, prescribed by physicians for patients who are experiencing symptoms that may be attributable to cardiac arrhythmia. Shortness of breath and palpitations are examples of these symptoms. This device may be worn for a period of days or weeks - whatever time is necessary to capture and record the ECG. The device consists of the SAVI Wireless event monitor, patient cable, and off the shelf cellular telephone. The device can be used with accessories, including a belt clip, lanyard, and PC interface cable.
More Information

K#043454

Not Found

No
The description focuses on the device's function as an ambulatory ECG recorder and transmitter, with no mention of AI or ML for analysis or interpretation.

No
The device records and transmits ECG signals for diagnostic purposes; it does not directly treat or alleviate a medical condition.

Yes

The device records and transmits ECG signals for patients experiencing symptoms attributable to cardiac arrhythmia, which is a process of identifying a medical condition.

No

The device description explicitly states that the device consists of hardware components including the event monitor, patient cable, and off-the-shelf cellular telephone.

Based on the provided information, this device is not an IVD (In Vitro Diagnostic).

Here's why:

  • IVD Definition: In vitro diagnostics are tests performed on samples taken from the human body, such as blood, urine, or tissue, to detect diseases, conditions, or infections.
  • Device Function: The SAVI Wireless PM500 records and transmits ambulatory ECG signals. This is a measurement of electrical activity of the heart, which is a physiological signal obtained directly from the patient's body, not from a sample taken from the body.
  • Intended Use: The intended use is to record ECG signals for patients experiencing symptoms potentially related to cardiac arrhythmia. This is a diagnostic tool that monitors a physiological process in vivo.

Therefore, the SAVI Wireless PM500 falls under the category of in vivo diagnostic devices or medical devices for physiological monitoring, not in vitro diagnostics.

N/A

Intended Use / Indications for Use

The SAVI Wireless Model PM500, is a pager-sized, hand-held or patient worn device designed specifically to record and transmit ambulatory ECG signals. The device can be worn for days or weeks, as it is intended for use by patients who are experiencing symptoms that are transient and infrequent in nature. Since the SAVI Wireless is patient-activated, the device is not intended for patients who are unable to activate the Record switch when they are experiencing a symptom.
The SAVI Wireless PM500, is a pager-sized, handheld or patient worn device designed specifically to record and transmit ambulatory ECG signals. The device can be worn for days or weeks, as it is intended for use by patients who are experiencing symptoms that are transient and infrequent in nature.

Product codes (comma separated list FDA assigned to the subject device)

DRG

Device Description

The SAVI Wireless Model PM500, is a small, auto triggered, hand-held device, prescribed by physicians for patients who are experiencing symptoms that may be attributable to cardiac arrhythmia. Shortness of breath and palpitations are examples of these symptoms. This device may be worn for a period of days or weeks - whatever time is necessary to capture and record the ECG.
The device consists of the SAVI Wireless event monitor, patient cable, and off the shelf cellular telephone. The device can be used with accessories, including a belt clip, lanyard, and PC interface cable.

Mentions image processing

Not Found

Mentions AI, DNN, or ML

Not Found

Input Imaging Modality

Not Found

Anatomical Site

Not Found

Indicated Patient Age Range

Not Found

Intended User / Care Setting

Not Found

Description of the training set, sample size, data source, and annotation protocol

Not Found

Description of the test set, sample size, data source, and annotation protocol

Not Found

Summary of Performance Studies (study type, sample size, AUC, MRMC, standalone performance, key results)

Non-Clinical Tests: All testing performed on the SAVI Wireless was derived from the risk assessment which evaluated the effects of the feature changes. Testing included IEC 60601-1, IEC 60601-1-2, and environmental and software validation testing.
Clinical Tests: Not Applicable

Key Metrics (Sensitivity, Specificity, PPV, NPV, etc.)

Not Found

Predicate Device(s): If the device was cleared using the 510(k) pathway, identify the Predicate Device(s) K/DEN number used to claim substantial equivalence and list them here in a comma separated list exactly as they appear in the text. List the primary predicate first in the list.

K#043454

Reference Device(s): Identify the Reference Device(s) K/DEN number and list them here in a comma separated list exactly as they appear in the text.

Not Found

Predetermined Change Control Plan (PCCP) - All Relevant Information for the subject device only (e.g. presence / absence, what scope was granted / cleared under the PCCP, any restrictions, etc).

Not Found

§ 870.2910 Radiofrequency physiological signal transmitter and receiver.

(a)
Identification. A radiofrequency physiological signal transmitter and receiver is a device used to condition a physiological signal so that it can be transmitted via radiofrequency from one location to another, e.g., a central monitoring station. The received signal is reconditioned by the device into its original format so that it can be displayed.(b)
Classification. Class II (performance standards).

0

pg 6f3

OCT 2 6 2009

EXHIBIT #1

510(K) SUMMARY

This summary of 510(k) safety and effectiveness information is being submitted in accordance with the requirements of SMDA 1990 and 21 CFR §807.92.

The assigned 510(k) number is: KC910960

Submitter's Identification: 1.

Medicomp, Inc. 7845 Ellis Road Melbourne, Florida 32904

Date Summary Prepared: May 8, 2009

Contact: Mr. Michael Thomas

2. Name of the Device:

SAVI Wireless Model PM500

3. Predicate Device Information:

K#043454, CardioPAL SAVI (Model PM410) Event/Loop Recorder, Medicomp, Inc.

4. Device Description:

The SAVI Wireless Model PM500, is a small, auto triggered, hand-held device, prescribed by physicians for patients who are experiencing symptoms that may be attributable to cardiac arrhythmia. Shortness of breath and palpitations are examples of these symptoms. This device may be worn for a period of days or weeks - whatever time is necessary to capture and record the ECG.

The device consists of the SAVI Wireless event monitor, patient cable, and off the shelf cellular telephone. The device can be used with accessories, including a belt clip, lanyard, and PC interface cable.

5. Intended Use:

The SAVI Wireless Model PM500, is a pager-sized, hand-held or patient worn device designed specifically to record and transmit ambulatory ECG signals. The device can be worn for days or weeks, as it is intended for use by patients

1

K0916896
pg 2 of 3

who are experiencing symptoms that are transient and infrequent in nature. Since the SAVI Wireless is patient-activated, the device is not intended for patients who are unable to activate the Record switch when they are experiencing a symptom.

દ. Comparison to Predicate Device:

The following comparison chart outlines similarities and differences between the subject device and the predicate device:

| Features | Predicate Device
CardioPAL SAVI (PM410) | Subject Device
SAVI Wireless (PM500) |
|-------------------|----------------------------------------------------------------------------------|----------------------------------------------------------------------------------|
| ECG Storage | 20 Minutes | 20 Minutes |
| On Board Analysis | Yes | Yes |
| ECG Input | 1 Channel 2 Wires
1 Channel 3 Wires
2 Channel 3 Wires
2 Channel 5 Wires | 1 Channel 2 Wires
1 Channel 3 Wires
2 Channel 3 Wires
2 Channel 5 Wires |
| User Interface | Audio Beeper
2 Line x 16 Character LCD
3 Buttons | Audio Beeper
2 Buttons
Cellular Telephone |
| PC Interface | Trans-telephonic
USB | Cellular Network
Bluetooth
USB |
| Case | Plastic | Plastic |
| EC38 Type | Type 3 | Type 3 |
| Battery | 1 AA | 1 AA
1 Rechargeable |

6. Discussion of Non-Clinical Tests Performed for Determination of Substantial Equivalence:

All testing performed on the SAVI Wireless was derived from the risk assessment which evaluated the effects of the feature changes. Testing included IEC 60601-1, IEC 60601-1-2, and environmental and software validation testing.

Discussion of Clinical Tests Performed: 8.

Not Applicable

9. Conclusions:

The subject device, SAVI Wireless Model PM500, has identical indications for use as the predicate device, CardioPAL SAVI Model PM410. The bench testing

2

K091696
pg 3 of 3

contained in our submission demonstrates that there are no differences in their technological characteristics, thereby not raising any new issues of safety or effectiveness. Thus, the SAVI Wireless Model PM500, is substantially equivalent to the predicate device, the CardioPAL SAVI Model PM410.

3

DEPARTMENT OF HEALTH & HUMAN SERVICES

Image /page/3/Picture/1 description: The image shows the logo for the U.S. Department of Health & Human Services. The logo consists of a circular seal with the text "DEPARTMENT OF HEALTH & HUMAN SERVICES • USA" arranged around the perimeter. Inside the circle is a stylized image of an eagle or other bird-like figure with its wings spread.

Public Health Service

Food and Drug Administration 10903 New Hampshire Avenue Document Control Room W-066-0609 Silver Spring, MD 20993-0002

OCT 2 6 2009

Medicomp, Inc. c/o Ms. Susan D. Goldstein-Falk mdi Consultants Inc 55 Northern Blvd., Suite 200 Great Neck, NY 11021

Re: K091696

Trade/Device Name: SAVI Wireless Model PM500 Regulation Number: 21 CFR 870.2910 Regulation Name: Radiofrequency Physiological Signal Transmitter and Receiver Regulatory Class: Class II (two) Product Code: DRG Dated: September 30, 2009 Received: October 1, 2009

Dear Ms. Goldstein-Falk:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

4

Page 2 - Ms. Susan D. Goldstein-Falk

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807): labeling (21 CFR Part 801): medical device reporting (reporting of medical device-related adverse events) (21 CFR 803); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please go to http://www.fda.gov/AboutFDA/CentersOffices/CDRH/CDRHOffices/ucm115809.htm for the Center for Devices and Radiological Health's (CDRH's) Office of Compliance. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). For questions regarding the reporting of adverse events under the MDR regulation (21 CFR Part 803), please go to

http://www.fda.gov/MedicalDevices/Safety/ReportaProblem/default.htm for the CDRH's Office of Surveillance and Biometrics/Division of Postmarket Surveillance.

You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (301) 796-7100 or at its Internet address

http://www.fda.gov/MedicalDevices/ResourcesforYou/Industry/default.htm.

Sincerely yours,

W.M.P.

St Bram D. Zuckerman, M.D. Director Division of Cardiovascular Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

5

Exhibit B

Page 1 of

510(k) Number (if known): K091696

Device Name: SAVI Wireless Model PM500

Indications For Use:

The SAVI Wireless PM500, is a pager-sized, handheld or patient worn device designed specifically to record and transmit ambulatory ECG signals. The device can be worn for days or weeks, as it is intended for use by patients who are experiencing symptoms that are transient and infrequent in nature.

Prescription Use × (Per 21 CFR 801 Subpart D)

OR

Over-The Counter Use (21 CFT 807 Subpart C)

(PLEASE DO NOT WRITE BELOW THIS LINE-CONTINUE ON ANOTHER PAGE IF NEEDED)

Concurrence of CDRH, Office of Device Evaluation (ODE)

W.W. West

(Division Sign-Off) Division of Cardiovascular Devices

510(k) Number K091696