K Number
K070448
Device Name
CARDIOMEMS ENDOSURE WIRELESS AAA PRESSURE MEASUREMENT SYSTEM, MODEL ADS-1001
Manufacturer
Date Cleared
2007-03-15

(28 days)

Product Code
Regulation Number
870.2855
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdparty
Intended Use
The CardioMEMS EndoSure™ Wireless AAA Pressure Measurement System is intended for measuring intrasac pressure during endovascular abdominal aortic aneurysm (AAA) repair and may be used as an adjunctive tool in the detection of intraoperative endoleaks. It also may be used for measuring intrasac pressure during thoracic aortic aneurysm (TAA) repair.
Device Description
The CardioMEMS EndoSure™ Wireless AAA Pressure Measurement System is designed to monitor pressure within the sac of a repaired aneurysm during endovascular stent graft placement. The CardioMEMS EndoSure™ Wireless AAA Pressure Measurement System includes: - The CardioMEMS EndoSure™ Sensor with radio-opaque markings (implant) - A sterile Delivery System (pre-loaded with the CardioMEMS EndoSure™ Sensor) - CardioMEMS EndoSure™ Electronics System
More Information

NQH

Not Found

No
The summary describes a system for measuring pressure using a sensor and electronics, with no mention of AI or ML in the intended use, device description, or performance studies.

No.
The device is used for measuring intrasac pressure and detecting endoleaks, which are diagnostic/monitoring functions, not therapeutic interventions.

Yes
The device is intended for "measuring intrasac pressure during endovascular abdominal aortic aneurysm (AAA) repair and may be used as an adjunctive tool in the detection of intraoperative endoleaks." Detecting endoleaks is a diagnostic function.

No

The device description explicitly lists hardware components: a sensor (implant), a delivery system, and an electronics system.

Based on the provided information, the CardioMEMS EndoSure™ Wireless AAA Pressure Measurement System is not an IVD (In Vitro Diagnostic).

Here's why:

  • IVD Definition: In Vitro Diagnostics are medical devices used to examine specimens taken from the human body, such as blood, urine, or tissue, to provide information for diagnosis, monitoring, or screening.
  • Device Function: The CardioMEMS EndoSure™ system is designed to measure pressure directly within the sac of a repaired aneurysm inside the patient's body. It is an implantable sensor and associated electronics used during a surgical procedure (endovascular repair).
  • No Specimen Analysis: The system does not analyze any specimens taken from the body. It measures a physiological parameter (pressure) within the body.

Therefore, the CardioMEMS EndoSure™ Wireless AAA Pressure Measurement System falls under the category of an implantable medical device used for physiological monitoring, not an In Vitro Diagnostic.

N/A

Intended Use / Indications for Use

The CardioMEMS EndoSure™ Wireless AAA Pressure Measurement System is intended for measuring intrasac pressure during endovascular abdominal aortic aneurysm (AAA) repair and may be used as an adjunctive tool in the detection of intraoperative endoleaks. It also may be used for measuring intrasac pressure during thoracic aortic aneurysm (TAA) repair.

Product codes

NQH

Device Description

The CardioMEMS EndoSure™ Wireless AAA Pressure Measurement System is designed to monitor pressure within the sac of a repaired aneurysm during endovascular stent graft placement. The CardioMEMS EndoSure™ Wireless AAA Pressure Measurement System includes:

  • The CardioMEMS EndoSure™ Sensor with radio-opaque markings (implant) l
  • A sterile Delivery System (pre-loaded with the CardioMEMS EndoSure™ । Sensor)
  • CardioMEMS EndoSure™ Electronics System ।

The Sensor is implanted in the AAA or TAA sac during the time of stent graft deployment and is left in place in the excluded portion of the aneurysm as a permanent implant. The main body of the Sensor is manufactured from fused silica coated in silicone. Nitinol loops extend from the Sensor body. Radiopaque marker bands at each end of the Sensor body allow visualization of the device under fluoroscopy.

The Sensor is interrogated using the antenna of the EndoSure Electronics System. The antenna is placed over the patient's abdomen in the area of the Sensor. Once the signal is acquired, a pressure waveform and numerical pressure data are displayed on the touch-screen. A printout of the data and waveform is generated from a thermal printer which is incorporated in the Electronics.

Mentions image processing

Not Found

Mentions AI, DNN, or ML

Not Found

Input Imaging Modality

Not Found

Anatomical Site

abdominal aortic aneurysm (AAA), thoracic aortic aneurysm (TAA)

Indicated Patient Age Range

Not Found

Intended User / Care Setting

Not Found

Description of the training set, sample size, data source, and annotation protocol

Not Found

Description of the test set, sample size, data source, and annotation protocol

Not Found

Summary of Performance Studies

Testing has shown the EndoSure Sensor with Delivery System to be biocompatible and compatible with MRI, ultrasound, pacemakers and external defibrillators. Bench testing confirms that the device functions per its specifications.

Key Metrics

Not Found

Predicate Device(s)

CardioMEMS EndoSure™ Wireless AAA Pressure Measurement System

Reference Device(s)

Not Found

Predetermined Change Control Plan (PCCP) - All Relevant Information

Not Found

§ 870.2855 Implantable Intra-aneurysm Pressure Measurement System.

(a)
Identification. Implantable intra-aneurysm pressure measurement system is a device used to measure the intra-sac pressure in a vascular aneurysm. The device consists of a pressure transducer that is implanted into the aneurysm and a monitor that reads the pressure from the transducer.(b)
Classification. Class II (special controls). The special control is FDA's guidance document entitled “Class II Special Controls Guidance Document: Implantable Intra-Aneurysm Pressure Measurement System.” See § 870.1 (e) for the availability of this guidance document.

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510(k) Summary

A. Submitter's Information

Submitter's Name: CardioMEMS. Inc. Submitter's Address: 75 Fifth St, NW Suite 440 Atlanta, GA 30308

Contact Person: Grace Powers Telephone Number: (404) 920-6719 Fax Number: (404) 885-9974

Date of Preparation: February 14, 2007

  • B. Trade Name: CardioMEMS EndoSure™ Wireless AAA Pressure Measurement System
    Common Name: AAA Pressure Measurement System

  • Classification Name: Implantable Intra-aneurysm Pressure Measurement System

  • C. Predicate Devices: CardioMEMS EndoSure™ Wireless AAA Pressure Measurement System

  • D. Device Description

The CardioMEMS EndoSure™ Wireless AAA Pressure Measurement System is designed to monitor pressure within the sac of a repaired aneurysm during endovascular stent graft placement. The CardioMEMS EndoSure™ Wireless AAA Pressure Measurement System includes:

  • The CardioMEMS EndoSure™ Sensor with radio-opaque markings (implant) l
  • A sterile Delivery System (pre-loaded with the CardioMEMS EndoSure™ । Sensor)
  • CardioMEMS EndoSure™ Electronics System ।
  • E. Intended Use:

The CardioMEMS EndoSure™ Wireless AAA Pressure Measurement System is intended for measuring intrasac pressure during endovascular abdominal aortic aneurysm (AAA) repair and may be used as an adjunctive tool in the detection of intraoperative endoleaks. It also may be used for measuring intrasac pressure during thoracic aortic aneurysm (TAA) repair.

MAR 1 5 2007

1

  • F. Technological Characteristics Summary
    The Sensor is implanted in the AAA or TAA sac during the time of stent graft deployment and is left in place in the excluded portion of the aneurysm as a permanent implant. The main body of the Sensor is manufactured from fused silica coated in silicone. Nitinol loops extend from the Sensor body. Radiopaque marker bands at each end of the Sensor body allow visualization of the device under fluoroscopy.

The Sensor is interrogated using the antenna of the EndoSure Electronics System. The antenna is placed over the patient's abdomen in the area of the Sensor. Once the signal is acquired, a pressure waveform and numerical pressure data are displayed on the touch-screen. A printout of the data and waveform is generated from a thermal printer which is incorporated in the Electronics.

ে. Performance Data

Testing has shown the EndoSure Sensor with Delivery System to be biocompatible and compatible with MRI, ultrasound, pacemakers and external defibrillators. Bench testing confirms that the device functions per its specifications.

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DEPARTMENT OF HEALTH & HUMAN SERVICES

Image /page/2/Picture/1 description: The image shows the logo for the U.S. Department of Health & Human Services. The logo consists of a stylized eagle with three lines forming its body and wing. The text "DEPARTMENT OF HEALTH & HUMAN SERVICES - USA" is arranged in a circular fashion around the eagle. The text is in all caps and is written in a simple, sans-serif font.

Public Health Service

Food and Drug Administration 9200 Corporate Boulevard Rockville MD 20850

Cardiomems, Inc. c/o Ms. Grace Powers Regulatory Affairs Specialist 75 Fifth Street, NW, Suite 440 Atlanta, GA 30308

MAR 1 5 2007

Re: K070448

CardioMEMS EndoSure AAA Pressure Measurement System Regulation Number: 21 CFR 870.2855 Regulation Name: Implantable Aneurysm Pressure Sensor Regulatory Class: Class II (Two) Product Code: NQH Dated: February 14, 2007 Received: February 15, 2007

Dear Ms. Powers:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to such additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

3

Page 2 - Ms. Grace Powers

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050. This letter will allow you to begin marketing your device as described in your Section 510(k) premarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus, permits your device to proceed to the market.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please contact the Office of Compliance at (240) 276-0120. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (240) 276-3150 or at its Internet address http://www.fda.gov/cdrl/industry/support/index.html.

Sincerely yours.

una R.v.dunes

Bram D. Zuckerman, M.D. Director Division of Cardiovascular Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

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INDICATIONS FOR USE

510(k) Number (if known): Not known K (070ЧЧВ

Device Name:

CardioMEMS EndoSure™ Wireless AAA Pressure Measurement System

Indications for Use:

The CardioMEMS EndoSure™ Wireless AAA Pressure Measurement System is intended for measuring intrasac pressure during endovascular abdominal aortic aneurysm (AAA) repair and may be used as an adjunctive tool in the detection of intraoperative endoleaks. It also may be used for measuring intrasac pressure during thoracic aortic aneurysm (TAA) repair.

Prescription Use X (Part 21 CRF 801 Subpart D) AND/OR

Over-The-Counter Use (Part 21 CFR 807 Subpart C)

(PLEASE DO NOT WRITE BELOW THIS LINE-CONTINUE ON ANOTHER PAGE IF NEEDED)

Dana R. Valines

(Division Sign-Off) (Division Sign-Off)
Division on Cardiovascular Devices

510(k) Number K070448