K Number
K070268
Device Name
SIGNATURE EDITION INFUSION SYSTEM, MODELS 710X, 720X
Date Cleared
2007-02-23

(25 days)

Product Code
Regulation Number
880.5725
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP Authorized
Intended Use
The Signature Edition® Infusion System (Models 710X and 720X) is intended for use in today's growing professional healthcare environment including healthcare facilities, home care, and medical transport that utilize infusion systems for the delivery of fluids, medications, blood and blood products. The Signature Edition® Infusion System is indicated for continuous or intermittent delivery through clinically acceptable routes of administration such as intravenous (IV), intra-arterial (IA), subcutaneous, epidural, enteral, or irrigation of fluid spaces.
Device Description
The subject of this Special 510(k) submission is the Signature Edition® Infusion System Models 710X and 720X. This device is essentially the same as the originally submitted predicate device, the Signature Edition® Infusion System (submitted as the Models EZ 1 and EZ 2 Infusion Pumps, K931549, October 12, 1993), with the exception of the device modification provided in this submission. The electrical volumetric pumps are used to control the rate or monitor the flow of solution or medication for delivery of drugs, fluids, and blood products.
More Information

No
The document explicitly states "Mentions AI, DNN, or ML: Not Found" and the description focuses on electrical volumetric pumps controlling flow, not AI/ML capabilities.

Yes
The device is used for the "delivery of fluids, medications, blood and blood products" through "clinically acceptable routes," which directly constitutes therapeutic use.

No

The device is an infusion system designed for the delivery of fluids, medications, blood, and blood products, not for diagnosing medical conditions.

No

The device description explicitly states it is an "electrical volumetric pump," which is a hardware component, not solely software.

Based on the provided text, this device is not an IVD (In Vitro Diagnostic).

Here's why:

  • Intended Use: The intended use describes the delivery of fluids, medications, blood, and blood products into a patient. This is an in vivo (within a living organism) application, not an in vitro (in glass or outside the body) diagnostic test.
  • Device Description: The device is described as an "electrical volumetric pump" used to control the rate or monitor the flow of solutions or medications for delivery. This aligns with an infusion system, not a diagnostic device that analyzes samples.
  • Lack of IVD Characteristics: The description does not mention any of the typical characteristics of an IVD, such as analyzing biological samples (blood, urine, tissue), detecting analytes, or providing diagnostic information.

Therefore, the Signature Edition® Infusion System is an infusion pump used for therapeutic delivery, not an in vitro diagnostic device.

N/A

Intended Use / Indications for Use

The Signature Edition® Infusion System is intended for use in today's growing professional healthcare environment including healthcare facilities, home care, and medical transport that utilize infusion systems for the delivery of fluids, medications, blood and blood products.

The Signature Edition® Infusion System is indicated for continuous or intermittent delivery through clinically acceptable routes of administration such as intravenous (IV), intra-arterial (IA), subcutaneous, epidural, enteral, or irrigation of fluid spaces.

Product codes

FRN

Device Description

The subject of this Special 510(k) submission is the Signature Edition® Infusion System Models 710X and 720X. This device is essentially the same as the originally submitted predicate device, the Signature Edition® Infusion System (submitted as the Models EZ 1 and EZ 2 Infusion Pumps, K931549, October 12, 1993), with the exception of the device modification provided in this submission. Other prior submissions include K032147 (Signature Edition Infusion System), which covered minor aggregate changes to the Signature Edition Infusion System and included all Signature Edition models (700X, 710X, 720X, 713X and 723X).

The same device modification provided in this submission was also submitted for the Signature Edition® Gold Infusion System, Models 713X and 723X (K063288) and was cleared to market on November 28, 2006.

The electrical volumetric pumps are used to control the rate or monitor the flow of solution or medication for delivery of drugs, fluids, and blood products. Infusion pumps have been proven to be useful in applications such as continuous epidural anesthesia, administration of IV cardiovascular drugs, chemotherapy, and blood transfusions.

Mentions image processing

Not Found

Mentions AI, DNN, or ML

Not Found

Input Imaging Modality

Not Found

Anatomical Site

through clinically acceptable routes of administration such as intravenous (IV), intra-arterial (IA), subcutaneous, epidural, enteral, or irrigation of fluid spaces.

Indicated Patient Age Range

Not Found

Intended User / Care Setting

professional healthcare environment including healthcare facilities, home care, and medical transport that utilize infusion systems

Description of the training set, sample size, data source, and annotation protocol

Not Found

Description of the test set, sample size, data source, and annotation protocol

Not Found

Summary of Performance Studies (study type, sample size, AUC, MRMC, standalone performance, key results)

Not Found

Key Metrics (Sensitivity, Specificity, PPV, NPV, etc.)

Not Found

Predicate Device(s)

K931549

Reference Device(s)

K032147, K063288

Predetermined Change Control Plan (PCCP) - All Relevant Information

Not Found

§ 880.5725 Infusion pump.

(a)
Identification. An infusion pump is a device used in a health care facility to pump fluids into a patient in a controlled manner. The device may use a piston pump, a roller pump, or a peristaltic pump and may be powered electrically or mechanically. The device may also operate using a constant force to propel the fluid through a narrow tube which determines the flow rate. The device may include means to detect a fault condition, such as air in, or blockage of, the infusion line and to activate an alarm.(b)
Classification. Class II (performance standards).

0

CARDINAL HEALTH, ALARIS PRODUCTS

K070268

ATTACHMENT D

FEB 2 3 2007

SUMMARY OF SAFETY AND EFFECTIVENESS

Cardinal Health Alaris Products

Signature Edition® Infusion System

Models 710X and 720X

SUBMITTER'S NAME: Cardinal Health 303, Inc. dba Cardinal Health, Alaris Products 10221 Wateridge Circle San Diego, CA 92121-2772 (858) 458-7830 (858) 458-6114 FAX

CONTACT PERSON: Stacy L. Lewis

Principal Regulatory Affairs Specialist

DATE PREPARED: January 26, 2007

Proprietary Name: DEVICE NAME: Signature Edition® Infusion System Common Name: Infusion Pump Classification Name: Pump, Infusion, FRN (880.5725)

PREDICATE DEVICE: Signature Edition® Infusion System (K931549), October 12, 1993

DEVICE DESCRIPTION

The subject of this Special 510(k) submission is the Signature Edition® Infusion System Models 710X and 720X. This device is essentially the same as the originally submitted predicate device, the Signature Edition® Infusion System (submitted as the Models EZ 1 and EZ 2 Infusion Pumps, K931549, October 12, 1993), with the exception of the device

1

SUMMARY OF SAFETY AND EFFECTIVENESS Page 2 of 3

modification provided in this submission. Other prior submissions include K032147 (Signature Edition Infusion System), which covered minor aggregate changes to the Signature Edition Infusion System and included all Signature Edition models (700X, 710X, 720X, 713X and 723X).

The same device modification provided in this submission was also submitted for the Signature Edition® Gold Infusion System, Models 713X and 723X (K063288) and was cleared to market on November 28, 2006.

The electrical volumetric pumps are used to control the rate or monitor the flow of solution or medication for delivery of drugs, fluids, and blood products. Infusion pumps have been proven to be useful in applications such as continuous epidural anesthesia, administration of IV cardiovascular drugs, chemotherapy, and blood transfusions.

SUBSTANTIAL EQUIVALENCE

With the exception of the device modification presented in this submission, the Signature Edition® Infusion System is essentially the same as the originally submitted predicate device. The intended use, principles of operation, fundamental scientific technology, method of manufacture, and application are essentially the same.

INTENDED USE

The intended use of this device has not changed from the original submissions in terms of content or intent:

The Signature Edition® Infusion System is intended for use in today's growing professional healthcare environment including healthcare facilities, home care, and medical transport that utilize infusion systems for the delivery of fluids, medications, blood and blood products.

070268

00171

2

SUMMARY OF SAFETY AND EFFECTIVENESS Page 3 of 3

The Signature Edition® Infusion System is indicated for continuous or intermittent delivery through clinically acceptable routes of administration such as intravenous (IV), intra-arterial (IA), subcutaneous, epidural, enteral, or irrigation of fluid spaces.

TECHNOLOGICAL CHARACTERISTICS

A comparison of the technological characteristics of the Signature Edition® Infusion System and the predicate devices has been performed. The results of this comparison demonstrate that the modified Signature Edition® Infusion System is equivalent in technological characteristics to the unmodified device and that the fundamental scientific technology of the predicate device has not been altered.

070268

3

Image /page/3/Picture/1 description: The image shows the logo for the U.S. Department of Health & Human Services. The logo consists of a stylized eagle with its wings spread, and the words "DEPARTMENT OF HEALTH & HUMAN SERVICES · USA" are arranged in a circular pattern around the eagle. The eagle is black, and the text is also black. The logo is simple and recognizable.

Food and Drug Administration 9200 Corporate Boulevard Rockville MD 20850

FEB 2 3 2007

Ms. Stacey L. Lewis Principal Regulatory Affairs Specialist Cardinal Health 303, Incorporated 10221 Wateridge Circle San Diego, California 92121-2772

Re: K070268

Trade/Device Name: Signature Edition® Infusion System Regulation Number: 21 CFR 880.5725 Regulation Name: Infusion Pump Regulatory Class: II Product Code: FRN Dated: January 26, 2007 Received: January 29, 2007

Dear Ms. Lewis:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to such additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

4

Page 2 - Ms. Lewis

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

This letter will allow you to begin marketing your device as described in your Section 510(k) premarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus, permits your device to proceed to the market.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please contact the Office of Compliance at (240) 276-0115. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (240) 276-3150 or at its Internet address http://www.fda.gov/cdrh/industry/support/index.html.

Sincerely yours,

Chiu Lin, Ph.D.

Director Division of Anesthesiology, General Hospital, Infection Control and Dental Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

5

Attachment B INDICATIONS FOR USE

510(k) Number:

K 070268 (To Be Assigned By FDA)

Device Trade Names:

Signature Edition® Infusion System

Indications For Use:

The Signature Edition® Infusion System (Models 710X and 720X) is intended for use in today's growing professional healthcare environment including healthcare facilities, home care, and medical transport that utilize infusion systems for the delivery of fluids, medications, blood and blood products.

The Signature Edition® Infusion System is indicated for continuous or intermittent delivery through clinically acceptable routes of administration such as intravenous (IV), intra-arterial (IA), subcutaneous, epidural, enteral, or irrigation of fluid spaces.

Prescription Use (Per 21 CFR 801.109)

Over-The-Counter Use

PLEASE DO NOT WRITE BELOW THIS LINE - CONTINUE ON ANOTHER PAGE IF NEEDED)

OR

Concurrence of CDRH, Office of Device Evaluation (ODE)

Anthony V. Watson

Anesthesiology, General Hospital,
Anesthesia, Medical Services

K970268

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