K Number
K060560
Device Name
ASCENSION PYROSPHERE CMC/TMT
Date Cleared
2006-05-05

(64 days)

Product Code
Regulation Number
888.3730
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdparty
Intended Use
The Ascension® PyroSphere™ CMC/TMT is intended to replace the joint between the first metacarpal and the trapezium in cases of rheumatoid arthritis, traumatic arthritis, osteoarthritis or post fracture deformation or bone loss which present as either a painful, unstable thumb, or a thumb with limited range of motion. The Ascension® PyroSphere™ CMC/TMT is also intended for use in the 4th /5th tarsometatarsal (TMT) joint involvement where degenerative or post-traumatic arthritis presents: - . decreased motion - . arthritic changes and/or subluxation - . unstable, stiff, or painful joints - degenerative joint disease of the midfoot associated with gout or pseudogout .
Device Description
The Ascension Ascension® PyroSphere™ CMC/TMT is a single-use, spherical, interpositional prosthesis intended for use in the carpometacarpal (CMC) basal thumb joint or the the 4" /5th tarsometatarsal (TMT) joint involvement. It articulates against recesses prepared in the base of the first metacarpal and the trapezium or the tarsometatarsal joint.
More Information

Not Found

No
The document describes a physical implant (a spherical prosthesis) and its intended use in joint replacement. There is no mention of software, algorithms, data processing, or any terms related to AI/ML.

Yes
The device is intended to treat and replace diseased or damaged joints, which is a therapeutic function.

No

The device is an interpositional prosthesis intended to replace a joint, which implies a therapeutic function rather than a diagnostic one.

No

The device description clearly states it is a "single-use, spherical, interpositional prosthesis," which is a physical implant, not software.

Based on the provided information, this device is not an IVD (In Vitro Diagnostic).

Here's why:

  • Intended Use: The intended use clearly describes a surgical implant designed to replace a joint in the hand or foot. This is a therapeutic device, not a diagnostic one.
  • Device Description: The description confirms it's a physical prosthesis intended for surgical implantation.
  • Lack of Diagnostic Elements: There is no mention of analyzing biological samples (blood, urine, tissue, etc.), detecting diseases or conditions in vitro, or providing information for diagnosis.

IVD devices are used to examine specimens from the human body to provide information for diagnosis, monitoring, or screening. This device does not fit that description.

N/A

Intended Use / Indications for Use

The Ascension® PyroSphere™ CMC/TMT is intended to replace the joint between the first metacarpal and the trapezium in cases of rheumatoid arthritis, traumatic arthritis, osteoarthritis or post fracture deformation or bone loss which present as either a painful, unstable thumb, or a thumb with limited range of motion.

The Ascension® PyroSphere™ CMC/TMT is also intended for use in the 4th /5th tarsometatarsal (TMT) joint involvement where degenerative or post-traumatic arthritis presents:

  • . decreased motion
  • . arthritic changes and/or subluxation
  • unstable, stiff, or painful joints .
  • degenerative joint disease of the midfoot associated with gout or pseudogout .

Product codes

KWD

Device Description

The Ascension Ascension® PyroSphere™ CMC/TMT is a single-use, spherical, interpositional prosthesis intended for use in the carpometacarpal (CMC) basal thumb joint or the the 4" /5th tarsometatarsal (TMT) joint involvement. It articulates against recesses prepared in the base of the first metacarpal and the trapezium or the tarsometatarsal joint.

Mentions image processing

Not Found

Mentions AI, DNN, or ML

Not Found

Input Imaging Modality

Not Found

Anatomical Site

carpometacarpal (CMC) basal thumb joint or the 4th /5th tarsometatarsal (TMT) joint

Indicated Patient Age Range

Not Found

Intended User / Care Setting

Prescription Use

Description of the training set, sample size, data source, and annotation protocol

Not Found

Description of the test set, sample size, data source, and annotation protocol

Not Found

Summary of Performance Studies (study type, sample size, AUC, MRMC, standalone performance, key results)

Not Found

Key Metrics (Sensitivity, Specificity, PPV, NPV, etc.)

Not Found

Predicate Device(s)

K030319, K042690

Reference Device(s)

Not Found

Predetermined Change Control Plan (PCCP) - All Relevant Information

Not Found

§ 888.3730 Toe joint phalangeal (hemi-toe) polymer prosthesis.

(a)
Identification. A toe joint phalangeal (hemi-toe) polymer prosthesis is a device made of silicone elastomer intended to be implanted to replace the base of the proximal phalanx of the toe.(b)
Classification. Class II.

0

510(k) SUMMARY

| SUBMITTER NAME: | Ascension Orthopedics, Inc.
87200 Cameron Road, C-100
Austin, TX 78754-3832 |
|------------------|-----------------------------------------------------------------------------------|
| CONTACT: | Glen Neally
Phone: (512) 836-5001 ext 1513
Fax: (512) 836-6933 |
| DATE OF SUMMARY: | 28 February 2006 |
| TRADE NAME: | Ascension® PyroSphere® |
| COMMON NAME: | pyrocarbon spherical implant |
| CLASSIFICATION: | 21 CFR §888.3730 |
| PRODUCT CODE: | KWD |
| PANEL: | Orthopedic |

K060560

MAY - 5 2005

PREDICATE DEVICES:

Orthosphere Ceramic Spherical Implant (K030319) Ascension® PyroSphere® (K042690)

DEVICE DESCRIPTION:

The Ascension Ascension® PyroSphere™ CMC/TMT is a single-use, spherical, interpositional prosthesis intended for use in the carpometacarpal (CMC) basal thumb joint or the the 4" /5th tarsometatarsal (TMT) joint involvement. It articulates against recesses prepared in the base of the first metacarpal and the trapezium or the tarsometatarsal joint.

INTENDED USE:

The Ascension® PyroSphere™ CMC/TMT) is intended to replace the joint between the first metacarpal and the trapezium in cases of rheumatoid arthritis, traumatic arthritis, osteoarthritis or post fracture deformation or bone loss which present as either a painful, unstable thumb, or a thumb with limited range of motion.

The Ascension® PyroSphere™ CMC/TMT is also intended for use in the 4th /5th

tarsometatarsal (TMT) joint involvement where degenerative or post-traumatic arthritis presents:

  • . decreased motion
  • . arthritic changes and/or subluxation
  • . unstable, stiff, or painful joints
  • degenerative joint disease of the midfoot associated with gout or pseudogout .

BASIS OF SUBSTANTIAL EQUIVALENCE:

A comparison of the design features as well as performance tests demonstrate that the Ascension® PyroSphere™ CMC/TMT is substantially equivalent to the predicate device.

1

Image /page/1/Picture/1 description: The image shows the logo for the Department of Health and Human Services (HHS). The logo features a stylized caduceus, a symbol often associated with medicine and healthcare, with three parallel lines forming the staff and a snake winding around it. The text "DEPARTMENT OF HEALTH AND HUMAN SERVICES . USA" is arranged in a circular pattern around the caduceus.

Food and Drug Administration 9200 Corporate Boulevard Rockville MD 20850

MAY -5 2006

Ascension Orthopedics, Inc. Mr. Glen Neally Vice President of QA/RA/CA 8700 Cameron Road, Suite C-100 Austin, Texas 78754-3832

Re: K060560

Trade/Device Name: Ascension® PyroSphere™ CMC/TMT Regulation Number: 21 CFR 888.3730 Regulation Name: Toe joint phalangeal (hemi-toe) polymer prosthesis Regulatory Class: Class II Product Code: KWD Dated: February 28, 2006 Received: March 2, 2006

Dear Mr. Neally:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to such additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); good manufacturing practice requirements as set

2

Page 2 - Mr. Glen Neally

forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050. This letter will allow you to begin marketing your device as described in your Section 510(k) premarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus, permits your device to proceed to the market.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please contact the Office of Compliance at (240) 276-0120. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (301) 443-6597 or at its Internet address http://www.fda.gov/cdrh/industry/support/index.html .

Sincerely yours.

Herbert Leonard co

for

Mark N. Melkerson Director Division of General, Restorative and Neurological Devices Office of Device Evaluation Center for Devices and Radiological Health

... ...

Enclosure

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Indications For Use

510(K) Number: K060560

Ascension® PyroSphere™ CMC/TMT Device Name:

Indications for Use:

The Ascension® PyroSphere™ CMC/TMT is intended to replace the joint between the first metacarpal and the trapezium in cases of rheumatoid arthritis, traumatic arthritis, osteoarthritis or post fracture deformation or bone loss which present as either a painful, unstable thumb, or a thumb with limited range of motion.

The Ascension® PyroSphere™ CMC/TMT is also intended for use in the 4th /5th tarsometatarsal (TMT) joint involvement where degenerative or post-traumatic arthritis

  • presents:
  • . decreased motion
  • . arthritic changes and/or subluxation
  • unstable, stiff, or painful joints .
  • degenerative joint disease of the midfoot associated with gout or pseudogout .

Prescription Use .X (Per 21 CFR 801.109)

OR

Over-The-Counter Use _

(PLEASE DO NOT WRITE BELOW THIS LINE - CONTINUE ON ANOTHER PAGE IF NECESSARY)

Concurrence of CDRH, Office of Device Evaluation (ODE)

Herbert Lerner

Division of General, Restorative and Neurological Devices

510(k) Number K060560