K Number
K042757
Device Name
VANGUARD SSK KNEE SYSTEM
Manufacturer
Date Cleared
2005-02-11

(130 days)

Product Code
Regulation Number
888.3560
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP Authorized
Intended Use
1. Painful and disabled knee joint resulting from osteoarthritis, rheumatoid arthritis, traumatic arthritis where one or more compartments are involved. 2. Correction of varus, valgus, or posttraumatic deformity. 3. Correction or revision of unsuccessful osteotomy, arthrodesis, or failure of previous joint replacement procedure. Vanguard™ SSK components are intended for cemented use only.
Device Description
The Vanguard™ SSK Knee System is a series of femoral components and tibial bearings designed to replace the articulating surfaces during knee replacement surgery.
More Information

K023546, K9151332

Not Found

No
The summary describes a traditional knee replacement system with no mention of AI/ML, image processing, or data-driven performance metrics.

Yes
The device is a knee replacement system intended to treat painful and disabled knee joints, correct deformities, and revise failed procedures, which are therapeutic interventions.

No
This device is a knee replacement system intended for surgical implantation to correct anatomical deformities and replace joint surfaces, not to diagnose medical conditions.

No

The device description explicitly states it is a "series of femoral components and tibial bearings," which are physical hardware components used in knee replacement surgery.

Based on the provided information, this device is not an IVD (In Vitro Diagnostic).

Here's why:

  • IVD Definition: In Vitro Diagnostics are medical devices used to perform tests on samples taken from the human body (like blood, urine, tissue) to provide information about a person's health.
  • Device Description: The description clearly states that the Vanguard™ SSK Knee System is a series of components designed to replace articulating surfaces during knee replacement surgery. This is a surgical implant, not a device used for testing samples.
  • Intended Use: The intended uses listed are all related to treating conditions of the knee joint through surgical intervention (replacing the joint, correcting deformities, revising previous surgeries). None of these involve testing biological samples.

Therefore, the Vanguard™ SSK Knee System is a surgical implant, not an In Vitro Diagnostic device.

N/A

Intended Use / Indications for Use

Indications for Use:

  1. Painful and disabled knee joint resulting from osteoarthritis, rheumatoid arthritis, traumatic arthritis where one or more compartments are involved.
  2. Correction of varus, valgus, or posttraumatic deformity.
  3. Correction or revision of unsuccessful osteotomy, arthrodesis, or failure of previous joint replacement procedure.

Vanguard ™ SSK components are intended for cemented use only.

Product codes

JWH

Device Description

The Vanguard™ SSK Knee System is a series of femoral components and tibial bearings designed to replace the articulating surfaces during knee replacement surgery.

Mentions image processing

Not Found

Mentions AI, DNN, or ML

Not Found

Input Imaging Modality

Not Found

Anatomical Site

Knee joint

Indicated Patient Age Range

Not Found

Intended User / Care Setting

Not Found

Description of the training set, sample size, data source, and annotation protocol

Not Found

Description of the test set, sample size, data source, and annotation protocol

Not Found

Summary of Performance Studies (study type, sample size, AUC, MRMC, standalone performance, key results)

Non-Clinical Testing: The performance data indicated that the Vanguard™ SSK Knee System is substantially equivalent to the predicate devices for the uses indicated.

Clinical Testing: Clinical testing was not required for these components to support substantial equivalence.

Key Metrics (Sensitivity, Specificity, PPV, NPV, etc.)

Not Found

Predicate Device(s)

K023546, K9151332

Reference Device(s)

Not Found

Predetermined Change Control Plan (PCCP) - All Relevant Information

Not Found

§ 888.3560 Knee joint patellofemorotibial polymer/metal/polymer semi-constrained cemented prosthesis.

(a)
Identification. A knee joint patellofemorotibial polymer/metal/polymer semi-constrained cemented prosthesis is a device intended to be implanted to replace a knee joint. The device limits translation and rotation in one or more planes via the geometry of its articulating surfaces. It has no linkage across-the-joint. This generic type of device includes prostheses that have a femoral component made of alloys, such as cobalt-chromium-molybdenum, and a tibial component or components and a retropatellar resurfacing component made of ultra-high molecular weight polyethylene. This generic type of device is limited to those prostheses intended for use with bone cement (§ 888.3027).(b)
Classification. Class II.

0

FEB 1 1 2005

K042757

510(k) Summary

| Applicant/Sponsor: | Biomet Manufacturing Corp.
56 East Bell Drive
P.O. Box 587
Warsaw, Indiana 46581-0587 |
|----------------------|----------------------------------------------------------------------------------------------------------------------------------------|
| Contact Person: | Gary Baker
Biomet Manufacturing Corp.
P.O. Box 587
Warsaw, Indiana 46581-0587
Phone: (574) 267-6639
FAX: (574) 372-1683 |
| Proprietary Name: | Vanguard™ SSK Knee System |
| Common Name: | Knee prosthesis |
| Classification Name: | Cemented semi-constrained polymer / metal / polymer knee
prosthesis (21 CFR § 888.3560) |

Legally Marketed Devices To Which Substantial Equivalence Is Claimed:

Maxim Accel (Vanguard) Knee System - K023546 (Biomet Inc.) Maximum Congruent Knee System - K9151332 (Biomet Inc.)

Device Description: The Vanguard™ SSK Knee System is a series of femoral components and tibial bearings designed to replace the articulating surfaces during knee replacement surgery.

Intended Use:

Indications for Use:

    1. Painful and disabled knee joint resulting from osteoarthritis, rheumatoid arthritis, traumatic arthritis where one or more compartments are involved.
    1. Correction of varus, valgus, or posttraumatic deformity.
    1. Correction or revision of unsuccessful osteotomy, arthrodesis, or failure of previous joint replacement procedure.

Vanguard™ SSK components are intended for cemented use only.

MAILING ADDRESS P.O. Box 587 Warsaw, IN 46581-0587

SHIPPING ADDRESS 56 E. Bell Drive Warsaw, IN 46582

OFFICE 574.267.6639

I·AX 574.267.8137

101

IE-MAIL biomet@hiomet.com

1

Summary of Technologies: The Vanguard™ SSK Knee System components have the same intended use (knee joint replacement), the same functional characteristics (knee joint articulation), and are manufactured from the same materials as the predicate devices.

Non-Clinical Testing: The performance data indicated that the Vanguard™ SSK Knee System is substantially equivalent to the predicate devices for the uses indicated.

Clinical Testing: Clinical testing was not required for these components to support substantial equivalence.

102

All trademarks are property of Biomet, Inc.

2

Image /page/2/Picture/1 description: The image shows the seal of the Department of Health & Human Services (HHS) of the United States. The seal features a stylized eagle with three stripes forming its body and wings. The text "DEPARTMENT OF HEALTH & HUMAN SERVICES - USA" is arranged in a circular pattern around the eagle.

Food and Drug Administration 9200 Corporate Boulevard Rockville MD 20850

FEB 1 1 2005

Mr. Gary Baker Regulatory Specialist Biomet Manufacturing Corp. P.O. Box 587 Warsaw, Indiana 46581-0587

Re: K042757 Trade/Device Name: Vanguard SSK Knee System Regulation Numbers: 21 CFR 888.3560 Regulation Names: Knee joint, patellofemorotibial, polymer/metal/polymer semiconstrained cemented prosthesis Regulatory Class: II Product Codes: JWH Dated: January 28, 2005 Received: January 31, 2005

Dear Mr. Baker:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food. Drug. and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (sec above) into either class II (Special Controls) or class III (PMA). it may be subject to such additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

3

Page 2 - Mr. Gary Baker

This letter will allow you to begin marketing your device as described in your Section 510(k) premarket notification. The FDA finding of substantial equivalence of your device to I legally marketed predicate device results in a classification for your device and thus, permitts your device to proceed to the market.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please contact the Office of Compliance at (240) 276-_. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (301) 443-6597 or at its Internet address http://www.fda.gov/cdrh/industry/support/index.html.

Sincerely yours,

Mark A. Millman

Celia M. Witten, Ph.D., M.D. Director Division of General, Restorative and Neurological Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

4

Indications For Use

510(k) Number (IF KNOWN): K042757

Device Name: Vanguard™ SSK Knee System

Indications for Use:

| 1. | Painful and disabled knee joint resulting from osteoarthritis,
rheumatoid arthritis, traumatic arthritis where one or more
compartments are involved. |
|----|-------------------------------------------------------------------------------------------------------------------------------------------------------------|
| 2. | Correction of varus, valgus, or posttraumatic deformity. |
| 3. | Correction or revision of unsuccessful osteotomy, arthrodesis, or
failure of previous joint replacement procedure. |

Vanguard™ SSK components are intended for cemented use only.

Prescription Use >> AND/OR (Per 21 CFR 801 Subpart D)

Over-the-Counter Use (21 CFR 807 Subpart C)

(PLEASE DO NOT WRITE BELOW THIS LINE – CONTINUE ON ANOTHER PAGE IF NEEDED)

Concurrence of CDRH, Office of Device Evaluation (ODE)

(Division Sign-Off)
Division of General, Restorative,
and Neurological Devices

510(k) Number
K042757