K Number
K023250
Device Name
LINICAL PROTEIN 2 CALIBRATION VERIFIERS LEVELS A-E FOR THE BECKMAN-COULTER IMMAGE
Date Cleared
2002-10-17

(17 days)

Product Code
Regulation Number
862.1660
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdparty
Intended Use
LiniCAL™ Protein 2 Calibration Verifiers Levels A – E for the Beckman-Coulter Immage™ is intended for use as an assayed quality control material for analysis.
Device Description
Not Found
More Information

Not Found

Not Found

No
The document describes a calibration material for a laboratory instrument and contains no mention of AI or ML.

No.
The device is intended for use as an assayed quality control material for analysis, not for treating or diagnosing a medical condition.

No
Explanation: The device is described as an "assayed quality control material for analysis," which indicates it is used to verify the performance of other laboratory tests, not to diagnose a condition itself.

No

The device is described as a "Calibration Verifier" material, which is a physical substance used for quality control in laboratory analysis. This indicates it is a material, not software.

Based on the provided information, the device is an IVD (In Vitro Diagnostic).

Here's why:

  • Intended Use: The intended use explicitly states it is "intended for use as an assayed quality control material for analysis." This indicates it is used in vitro (outside the body) to analyze a sample (likely a biological fluid) in a laboratory setting.
  • Device Name: "LiniCAL™ Protein 2 Calibration Verifiers Levels A – E for the Beckman-Coulter Immage™" suggests it's a reagent or material used with a specific diagnostic instrument (Beckman-Coulter Immage™) for calibration and verification purposes in a diagnostic test.

While the "Device Description" is not found, the intended use alone is sufficient to classify it as an IVD. Quality control materials and calibration verifiers used in laboratory diagnostic tests are considered IVDs.

N/A

Intended Use / Indications for Use

LiniCAL™ Protein 2 Calibration Verifiers Levels A – E for the Beckman-Coulter Immage™ is intended for use as an assayed quality control material for analysis.

Product codes

JJY

Device Description

Not Found

Mentions image processing

Not Found

Mentions AI, DNN, or ML

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Input Imaging Modality

Not Found

Anatomical Site

Not Found

Indicated Patient Age Range

Not Found

Intended User / Care Setting

Not Found

Description of the training set, sample size, data source, and annotation protocol

Not Found

Description of the test set, sample size, data source, and annotation protocol

Not Found

Summary of Performance Studies (study type, sample size, AUC, MRMC, standalone performance, key results)

Not Found

Key Metrics (Sensitivity, Specificity, PPV, NPV, etc.)

Not Found

Predicate Device(s)

Not Found

Reference Device(s)

Not Found

Predetermined Change Control Plan (PCCP) - All Relevant Information

Not Found

§ 862.1660 Quality control material (assayed and unassayed).

(a)
Identification. A quality control material (assayed and unassayed) for clinical chemistry is a device intended for medical purposes for use in a test system to estimate test precision and to detect systematic analytical deviations that may arise from reagent or analytical instrument variation. A quality control material (assayed and unassayed) may be used for proficiency testing in interlaboratory surveys. This generic type of device includes controls (assayed and unassayed) for blood gases, electrolytes, enzymes, multianalytes (all kinds), single (specified) analytes, or urinalysis controls.(b)
Classification. Class I (general controls). Except when intended for use in donor screening tests, quality control materials (assayed and unassayed) are exempt from the premarket notification procedures in subpart E of part 807 of this chapter subject to the limitations in § 862.9.

0

DEPARTMENT OF HEALTH & HUMAN SERVICES

Image /page/0/Picture/1 description: The image shows the logo for the Department of Health & Human Services - USA. The logo is a circular seal with the text "DEPARTMENT OF HEALTH & HUMAN SERVICES - USA" arranged around the perimeter. Inside the circle is a stylized image of three human profiles facing right, with flowing lines representing hair or movement.

Food and Drug Administration 098 Gaither Road Rockville MD 20850

OCT 1 7 2002

Ms. Carol Ruggiero Director of Regulatory Affairs CLINIQA Corporation 1432 South Mission Road Fallbrook, CA 92028

Re: K023250

Trade/Device Name: LiniCAL™ Protein 2 Calibration Verifiers Levels A – E Beckman-Coulter Immage™

Regulation Number: 21 CFR 862.1660

Regulation Name: Quality control material (assayed and unassayed) Regulatory Class: Class I

Product Code: JJY Dated: September 26, 2002 Received: September 30, 2002

Dear Ms. Ruggiero:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration. Ilsting of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to such additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA mav publish further announcements concerning your device in the Federal Register.

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

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This letter will allow you to begin marketing your device as described in your 510(k) premarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus, permits your device to proceed to the market.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801 and additionally 809.10 for in vitro diagnostic devices), please contact the Office of Compliance at (301) 594-4588. Additionally, for questions on the promotion and advertising of your device, please contact the Office of Compliance at (301) 594-4639. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR 807.97). Other general information on your responsibilities under the Act may be obtained from the Division of Small Manufacturers International and Consumer Assistance at its toll-free number (800) 638-2041 or (301) 443-6597 or at its internet address "http://www.fda.gov/cdrh/dsma/dsmamain.html".

Sincerely yours,

Steven Butman

Steven I. Gutman, M.D., M.B.A. Director Division of Clinical Laboratory-Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

2

510(k) Number (if known):

02 3250

Device Name: LiniCAL™ Protein 2 Calibration Verifiers Levels A - E for the Beckman-Coulter Immage™

Indications For Use:

LiniCAL™ Protein 2 Calibration Verifiers Levels A – E for the Beckman-Coulter Immage™ is intended for use as an assayed quality control material for analysis.

Dean Cooper
(Division Sign-Off)
Division of Clinical Laboratory Devices

510(k) Numbe

(PLEASE DO NOT WRITE BELOW THIS LINE - CONTINUE ON ANOTHER PAGE IF NEEDED)

Concurrence of CDRH, Office of Device Evaluation (ODE)

Prescription Use
(Per 21 CFR 801.109)

OR

Over-The-Counter Use